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How to get fromHarrisburg, Pa to Spartanburgby train, plane, bus, bus (Greyhound, Flixbus), car, or subway

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There are 9 ways to get from Harrisburg, Pa to Spartanburg by train, plane, bus, bus (Greyhound, Flixbus), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Greenville–Spartanburg International Airport

    best
    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane plane PHL - GSP
    5h 48m
    $220–890

  2. Drive 516.8 mi

    cheapest
    1. Drive from Harrisburg, Pa to Spartanburgcar car 516.8 mi
    9h 48m
    $95–137

  3. Bus, train

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the train from Washington Union Station to Spartanburg Stationtrain train Crescent
    14h 6m
    $157–332

  4. Bus

    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0430
    2. Take the bus from Baltimore Downtown Bus Station to Spartanburgbus bus Greyhound US0670
    16h 18m
    $108–202

  5. Fly Harrisburg International Airport to Charlotte Douglas International Airport, train

    1. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    6h 43m
    $199–1,163

  6. Train, train to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane plane BWI - GSP
    6h 40m
    $206–1,387

  7. Train, train to Ronald Reagan Washington National Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Greenville–Spartanburg International Airport (GSP)plane plane DCA - GSP
    7h 32m
    $251–1,644

  8. Train, subway to Washington Dulles International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Greenville–Spartanburg International Airport (GSP)plane plane IAD - GSP
    8h 5m
    $201–1,273

  9. Train, train to Ronald Reagan Washington National Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    4. Drive from Asheville-Airport-AVL to Spartanburgcar car
    8h
    $165–1,289

Harrisburg, Pa to Spartanburg by bus and train

Calendar7Weekly Services
Duration14h 6mAverage Duration
Ticket$157Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to Spartanburg.ExpandLaunch map view
  • Distance: 643.4 mi
  • Duration: 5h 48m

What companies run services between Harrisburg, Pa, PA, USA and Spartanburg, SC, USA?

You can take a bus from Harrisburg Bus Station to Spartanburg via Baltimore Downtown Bus Station and Spartanburg in around 16h 18m.

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