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How to get fromHarrisonburg to Florenceby bus, train, bus (Greyhound, Flixbus), car, plane, or taxi

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There are 6 ways to get from Harrisonburg to Florence by bus, train, bus (Greyhound, Flixbus), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Goodwin Transit Center to Washington Union Stationbus bus Highlands Rhythm / ...
    2. Take the train from Washington Union Station to Florence Stationtrain train Palmetto / ...
    12h 3m
    $158–303

  2. Drive 342.4 mi

    cheapest
    1. Drive from Harrisonburg to Florencecar car 342.4 mi
    6h 48m
    $63–91

  3. Bus

    1. Take the bus from Goodwin Transit Center to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    12h 59m
    $91–153

  4. Fly from Shenandoah Valley Regional Airport

    1. Fly from Shenandoah Valley Regional Airport (SHD) to Florence Regional Airport (FLO)plane plane SHD - FLO
    9h 32m
    $95–364

  5. Bus, train via Fayetteville

    1. Take the bus from Goodwin Transit Center to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    13h 21m
    $104–178

  6. Taxi to Charlottesville, fly

    1. Take the taxi from Harrisonburg to Charlottesville (CHO)taxi taxi
    2. Fly from Charlottesville (CHO) to Florence Regional Airport (FLO)plane plane CHO - FLO
    4h 45m
    $216–507

Harrisonburg to Florence by bus and train

Calendar14Weekly Services
Duration12h 3mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Harrisonburg to Florence.ExpandLaunch map view
  • Distance: 549.3 mi
  • Duration: 12h 3m

What companies run services between Harrisonburg, VA, USA and Florence, SC, USA?

You can take a bus from Goodwin Transit Center to Florence Bus Station via Washington Union Station and Raleigh Bus Station in around 12h 59m. Alternatively, American Airlines flies from Shenandoah Valley Regional Airport (SHD) to Florence Regional Airport (FLO) 3 times a day.

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