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How to get fromHartsville to Chicagoby bus, plane, bus (Greyhound, Flixbus), taxi, train, or car

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There are 10 ways to get from Hartsville to Chicago by bus, plane, bus (Greyhound, Flixbus), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Myrtle Beach, fly to Chicago Midway International Airport

    best
    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    6h 13m
    $169–516

  2. Drive  821.2 mi

    cheapest
    1. Drive from Hartsville to Chicagocar car 821.2 mi
    14h 43m
    $150–217

  3. Bus

    1. Take the bus from Florence Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    24h 14m
    $220–359

  4. Taxi, train (Amtrak)

    1. Take the taxi from Hartsville to Camden Stationtaxi taxi
    2. Take the train from Camden Station to Chicago Union Stationtrain train Floridian
    29h 33m
    $777–1,250

  5. Bus to Myrtle Beach, fly to Chicago O'Hare International Airport

    1. Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus bus
    2. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    6h 38m
    $154–436

  6. Taxi, bus to Charlotte Douglas International Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Hartsville to Camdentaxi taxi
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    7h 13m
    $257–561

  7. Taxi, bus to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    1. Take the taxi from Hartsville to Camdentaxi taxi
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    6h 47m
    $202–551

  8. Taxi, bus to Columbia, fly to Chicago O'Hare International Airport

    1. Take the taxi from Hartsville to Camdentaxi taxi
    2. Take the bus from Camden to Columbia, SCbus bus
    3. Fly from Columbia (CAE) to Chicago O'Hare International Airport (ORD)plane plane CAE - ORD
    7h 54m
    $203–489

  9. Taxi, bus to Charlotte Douglas International Airport, fly to South Bend, train

    1. Take the taxi from Hartsville to Camdentaxi taxi
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    4. Take the train from South Bend Airport to Van Buren St.train train
    8h 45m
    $244–733

  10. Bus to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Florence to Raleigh Bus Stationbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    8h 48m
    $242–339

Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) flights

Calendar22Weekly Planes
Duration3h 21mAverage Duration
Ticket$71Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hartsville to Chicago.ExpandLaunch map view
  • Distance: 843.2 mi
  • Duration: 6h 13m

What companies run services between Hartsville, SC, USA and Chicago, IL, USA?

You can take a vehicle from Hartsville to Chicago Bus Station via Florence Bus Station and Atlanta Bus Station in around 24h 14m.

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