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How to get fromHattiesburg to Knoxvilleby plane, train, bus, shuttle, or car

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There are 4 ways to get from Hattiesburg to Knoxville by plane, train, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Hattiesburg–Laurel Regional Airport

    best
    1. Fly from Hattiesburg–Laurel Regional Airport (PIB) to Mcghee Tyson Airport (TYS)plane plane PIB - TYS
    6h 21m
    $267–957

  2. Drive 487.4 mi

    cheapest
    1. Drive from Hattiesburg to Knoxvillecar car 487.4 mi
    8h 3m
    $89–129

  3. Train, bus, shuttle, drive

    1. Take the train from Hattiesburg Station to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    4. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    5. Drive from Hot Springs to Knoxvillecar car
    26h 19m
    $541–791

  4. Bus to Jackson/Vicksburg, fly

    1. Take the bus from Hattiesburg to Jacksonbus bus
    2. Fly from Jackson/Vicksburg (JAN) to Mcghee Tyson Airport (TYS)plane plane JAN - TYS
    6h 26m
    $221–761

Hattiesburg–Laurel Regional Airport (PIB) to Mcghee Tyson Airport (TYS) flights

Calendar16Weekly Planes
Duration7h 30mAverage Duration
Ticket$186Cheapest Price
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Questions & Answers

Map of how to get from Hattiesburg to Knoxville.ExpandLaunch map view
  • Distance: 453.3 mi
  • Duration: 6h 21m

What companies run services between Hattiesburg, MS, USA and Knoxville, TN, USA?

United Airlines flies from Hattiesburg–Laurel Regional Airport (PIB) to Mcghee Tyson Airport (TYS) twice daily.

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