There are 12 ways to get from Heidelberg to Assisi by train, plane, bus, train (Trenitalia), night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Florence Peretola Airport, train
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 48m€151–359Bus via Milan
cheapest- Take the bus from Heidelberg Pre Waypoint to Milanbus FlixBus N07 / ...
- Take the bus from Milan Lampugnano to Perugia Train Station Bus Stopbus Itabus
18h 28m€75–125Bus
- Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus 198 / ...
- Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
16h 34m€129–189Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Chiassotrain Ec
- Take the train from Chiasso to Firenze S. M. N.train Ec
- Take the train from Firenze S.M.N. to Assisitrain
17h 22m€170–431Train, night train
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain 55 / ...
- Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
- Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Assisitrain
21h 28m€105–250Train to Stuttgart Airport, fly to Fiumicino International Airport, train
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
- Take the train from Roma Termini to Assisitrain
9h 55m€102–240Train to Frankfurt, fly to Fiumicino International Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Assisitrain
9h 56m€76–213Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 13m€138–349Train to Frankfurt, fly to Pisa International Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
10h 59m€143–357Train to Frankfurt, fly to Venice Marco Polo Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
11h 56m€138–339Train to Frankfurt, fly to Verona Villafranca Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Verona Villafranca Airport (VRN)plane FRA - VRN
- Take the train from Verona Porta Nuova to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
12h 5m€173–404Drive 1,046.3 km
- Drive from Heidelberg to Assisicar 1,046.3 km
10h 8m€169–244
Heidelberg to Assisi by train and bus
Comparing Your Travel Options
The cheapest way to get from Heidelberg to Assisi is to bus via Milan which costs €75 - €130 and takes 18h 28m.
The fastest way to get from Heidelberg to Assisi is to train and fly which takes 9h 48m and costs €150 - €360.
No, there is no direct bus from Heidelberg to Assisi. However, there are services departing from Heidelberg Post Waypoint and arriving at Assisi via Karlsruhe Central Bus Station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 34m.
No, there is no direct train from Heidelberg to Assisi. However, there are services departing from Heidelberg, Hauptbahnhof and arriving at Assisi via Mannheim, Hauptbahnhof, Basel SBB, Chiasso and Firenze S.M.N.. The journey, including transfers, takes approximately 17h 22m.
The distance between Heidelberg and Assisi is 999 km. The road distance is 1046.3 km.
The best way to get from Heidelberg to Assisi without a car is to bus which takes 16h 34m and costs €120 - €190.
It takes approximately 9h 48m to get from Heidelberg to Assisi, including transfers.
Heidelberg to Assisi bus services, operated by FlixBus, depart from Heidelberg Post Waypoint station.
Heidelberg to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Heidelberg to Assisi is to bus which takes 16h 34m and costs €120 - €190. Alternatively, you can train, which costs €170 - €440 and takes 17h 22m.
What companies run services between Heidelberg, Germany and Assisi, Italy?
You can take a bus from Heidelberg Post Waypoint to Assisi via Karlsruhe Central Bus Station and Florence Villa Constanza Bus Station in around 16h 34m. Alternatively, you can take a train from Heidelberg, Hauptbahnhof to Via San Francesco via Mannheim, Hauptbahnhof, Basel SBB, Chiasso, Firenze S. M. N., Firenze S.M.N., Assisi, and Assisi Stazione in around 17h 22m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €120–600
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €170–650
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €65–300
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–120
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €140–550
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €150–550
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €80–300
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €130–480
Flights from Frankfurt to Verona Villafranca Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €160–600
Flights from Frankfurt to Verona Villafranca Airport via Munich
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- €170–600
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €45–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €16–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €16–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Heidelberg Post Waypoint to Karlsruhe central train station
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €4–7
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €14–22
- Website
- Flixbus
Bus from Heidelberg Pre Waypoint to Milan
- Ave. Duration
- 8h 56m
- Frequency
- 3 times a day
- Estimated price
- €45–75
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Booking & Getting There
Heidelberg to Assisi bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Heidelberg to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Heidelberg to Assisi is 1046 km. It takes approximately 10h 8m to drive from Heidelberg to Assisi.
There are 2389+ hotels available in Assisi.









