There are 8 ways to get from Heidelberg to Grenoble by train (TGV), bus, car, train, plane, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Grenobletrain Ter
9h 21m€131–266Bus
cheapest- Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus 198 / ...
- Take the bus from Karlsruhe central train station to Lyonbus
- Take the bus from Lyon to Grenoblebus 766 / ...
11h 18m€52–96Drive 630 km
- Drive from Heidelberg to Grenoblecar 630 km
6h 3m€101–146Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
6h 55m€140–386Train, bus
- Take the train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
- Take the train from Renens VD to Genève-Aéroporttrain Ic1 / ...
- Take the bus from Geneva - Airport Bus Station to Grenoble - Bus Stationbus
9h 49m€124–351Night train, bus, train
- Take the nighttrain from Heidelberg Hbf to Basel Sbbnighttrain Nj
- Take the bus from Basel SBB to Annecybus
- Take the train from Annecy to Grenobletrain K21
11h 1m€78–177Train to Frankfurt, fly to Geneva International Airport, bus, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
- Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
7h 45m€138–337Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane SXB - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
6h 54m€144–434
Heidelberg to Grenoble by train
Comparing Your Travel Options
The cheapest way to get from Heidelberg to Grenoble is to bus which costs €50 - €100 and takes 11h 18m.
The fastest way to get from Heidelberg to Grenoble is to drive which takes 6h 3m and costs €100 - €150.
No, there is no direct bus from Heidelberg to Grenoble. However, there are services departing from Heidelberg Post Waypoint and arriving at Grenoble via Karlsruhe central train station and Lyon. The journey, including transfers, takes approximately 11h 18m.
No, there is no direct train from Heidelberg to Grenoble. However, there are services departing from Heidelberg, Hauptbahnhof and arriving at Grenoble via Karlsruhe Hauptbahnhof, Strasbourg and Lyon Part Dieu. The journey, including transfers, takes approximately 9h 21m.
The distance between Heidelberg and Grenoble is 771 km. The road distance is 630 km.
The best way to get from Heidelberg to Grenoble without a car is to train which takes 9h 21m and costs €130 - €270.
It takes approximately 9h 21m to get from Heidelberg to Grenoble, including transfers.
Heidelberg to Grenoble bus services, operated by FlixBus, depart from Heidelberg Post Waypoint station.
Heidelberg to Grenoble train services, operated by Deutsche Bahn Regio (DB Regional), depart from Heidelberg, Hauptbahnhof station.
The best way to get from Heidelberg to Grenoble is to train which takes 9h 21m and costs €130 - €270. Alternatively, you can bus, which costs €50 - €100 and takes 11h 18m.
What companies run services between Heidelberg, Germany and Grenoble, France?
You can take a train from Heidelberg, Hauptbahnhof to Grenoble via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, Strasbourg, and Lyon Part Dieu in around 9h 21m. Alternatively, you can take a bus from Heidelberg Post Waypoint to Grenoble via Karlsruhe central train station and Lyon in around 11h 18m.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–500
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 40m
- When
- Monday and Wednesday
- Estimated price
- €80–250
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €100–230
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- €100–450
- Website
- airbus.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–250
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Saturday and Sunday
- Estimated price
- €160–500
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €140–440
- Website
- brusselsairlines.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–280
Flights from Frankfurt to Geneva International Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €120–300
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €650–1,400
- Website
- airfrance.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €55–340
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 34 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 34 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 43m
- Frequency
- 5 times a week
- Estimated price
- €35–150
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 34 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 27 min
- Frequency
- Every 4 hours
- Estimated price
- €9–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 27 min
- Frequency
- Every 4 hours
- Estimated price
- €9–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 27 min
- Frequency
- Every 4 hours
- Estimated price
- €9–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- Österreichische Bundesbahnen
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- Österreichische Bundesbahnen
- Phone
- +49 6131 4975 022
- [email protected]
- Website
- dbregiobus-mitte.de
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Once a week
- Estimated price
- €12–17
- Schedules at
- dbregiobus-mitte.de
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Once a week
- Estimated price
- €12–17
- Schedules at
- dbregiobus-mitte.de
Train from Heidelberg, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Once a week
- Estimated price
- €12–17
- Schedules at
- dbregiobus-mitte.de
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 13m
- Frequency
- 4 times a day
- Estimated price
- €100–150
- Website
- TGV inOui
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 11m
- Frequency
- Twice a week
- Estimated price
- €26–40
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 20m
- Frequency
- 6 times a week
- Estimated price
- €85–150
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €20–35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €12–20
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €20–35
- Website
- Oui.SNCF
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Once daily
- Estimated price
- €21–40
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- 6 times a week
- Estimated price
- €70–120
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- €60–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Genève-Aéroport
- Ave. Duration
- 44 min
- Frequency
- Every 20 minutes
- Estimated price
- €23–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Once a week
- Estimated price
- €45–55
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Heidelberg Hbf to Basel Sbb
- Ave. Duration
- 2h 47m
- Frequency
- Once daily
- Estimated price
- €23–95
- Website
- Nightjet
- Sleeper Carriage
- €85–95
- Couchette Carriage
- €55–65
- Seating Carriage
- €23–28
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Annecy to Grenoble
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- €30–45
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Heidelberg Post Waypoint to Karlsruhe central train station
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Website
- Flixbus
Bus from Karlsruhe central train station to Lyon
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Flixbus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €9–14
- Website
- Flixbus
Bus from Geneva - Airport Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- 4 times a day
- Estimated price
- €13–20
- Website
- Flixbus
Bus from Basel SBB to Annecy
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- €25–40
- Website
- Flixbus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- €8–12
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Karlsruhe central train station to Lyon
- Ave. Duration
- 8h 5m
- Frequency
- 4 times a day
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 45m
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- BlaBlaCar Bus
Bus from Geneva - Airport Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- BlaBlaCar Bus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–12
- Website
- BlaBlaCar Bus
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Heidelberg to Grenoble bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Heidelberg to Grenoble train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Yes, the driving distance between Heidelberg to Grenoble is 630 km. It takes approximately 6h 3m to drive from Heidelberg to Grenoble.
Book your Heidelberg to Grenoble train tickets online with Omio.
Book your Heidelberg to Grenoble bus tickets online with Omio and FlixBus.
There are 2317+ hotels available in Grenoble.


















































