There are 10 ways to get from Heidelberg to Palermo by train, plane, train (Trenitalia), car, car ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Palermo Airport
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
6h 52m€92–261Train, bus to Hahn, fly to Palermo Airport
cheapest- Take the train from Heidelberg, Hauptbahnhof to Mainz, Hauptbahnhoftrain
- Take the bus from Mainz, Hauptbahnhof to Hahnbus
- Fly from Hahn (HHN) to Palermo Airport (PMO)plane HHN - PMO
8h 30m€76–250Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
24h 51m€247–551Drive, car ferry
- Drive from Heidelberg to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
26h 35m€233–343Bus via Milan
- Take the bus from Heidelberg Pre Waypoint to Milanbus FlixBus N07 / ...
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
31h 51m€192–286Train, train to Allgäu Airport, Memmingen, fly to Palermo Airport
- Take the train from Heidelberg, Hauptbahnhof to Ulm Hauptbahnhoftrain
- Take the train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOBtrain
- Fly from Allgäu Airport, Memmingen (FMM) to Palermo Airport (PMO)plane FMM - PMO
8h 18m€77–333Train to Cologne Bonn Airport, fly to Palermo Airport
- Take the train from Mannheim, Hauptbahnhof to Köln Hbftrain
- Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane CGN - PMO
8h 9m€106–427Train to Frankfurt, fly to Catania–Fontanarossa Airport, bus
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
9h 16m€100–283Train, train to Nuremberg Airport, fly to Palermo Airport
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain
- Take the train from Hauptbahnhof to Nürnberg Hbftrain
- Fly from Nuremberg Airport (NUE) to Palermo Airport (PMO)plane NUE - PMO
9h 21m€118–340Bus
- Take the bus from Heidelberg Post Waypoint to Stuttgart Airport Busterminalbus N94 / ...
- Take the bus from Stuttgart Airport to Palermo Piazza Cairolibus
31h 54m€252–347
Heidelberg to Palermo by bus
Comparing Your Travel Options
The cheapest way to get from Heidelberg to Palermo is to train and fly which costs €75 - €340 and takes 8h 18m.
The fastest way to get from Heidelberg to Palermo is to train and fly which takes 6h 52m and costs €90 - €270.
No, there is no direct bus from Heidelberg to Palermo. However, there are services departing from Heidelberg Pre Waypoint and arriving at Palermo via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 31h 51m.
No, there is no direct train from Heidelberg to Palermo. However, there are services departing from Heidelberg, Hauptbahnhof and arriving at Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 24h 51m.
The distance between Heidelberg and Palermo is 1488 km.
The best way to get from Heidelberg to Palermo without a car is to train which takes 24h 51m and costs €240 - €550.
It takes approximately 6h 52m to get from Heidelberg to Palermo, including transfers.
Heidelberg to Palermo bus services, operated by FlixBus, depart from Heidelberg Pre Waypoint station.
Heidelberg to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Heidelberg to Palermo is to train which takes 24h 51m and costs €240 - €550. Alternatively, you can bus via Milan, which costs €190 - €290 and takes 31h 51m.
What companies run services between Heidelberg, Germany and Palermo, Italy?
You can take a train from Heidelberg, Hauptbahnhof to Palermo Centrale via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 24h 51m. Alternatively, you can take a bus from Heidelberg Pre Waypoint to Palermo via Milano, Autostazione Lampugnano in around 31h 51m.
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €75–280
Flights from Cologne Bonn Airport to Palermo Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Friday
- Estimated price
- €80–290
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Nuremberg Airport to Palermo Airport via Frankfurt
- Ave. Duration
- 5h
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €110–390
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €95–200
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €65–210
- Website
- ryanair.com
Flights from Allgäu Airport, Memmingen to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–210
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- €50–170
Flights from Cologne Bonn Airport to Palermo Airport via Bologna
- Ave. Duration
- 5h
- When
- Friday
- Estimated price
- €50–170
Flights from Hahn to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- €45–200
Flights from Nuremberg Airport to Palermo Airport
- Ave. Duration
- 2h 5m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- €65–200
- Website
- eurowings.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Saturday
- Estimated price
- €100–310
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Ulm Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 3 hours
- Estimated price
- €28–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOB
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- €8–18
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- €35–85
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Nürnberg Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Every 2 hours
- Estimated price
- €30–70
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 9m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOB
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €5–9
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Once a week
- Estimated price
- €13–16
- Schedules at
- DB ZugBus Regionalverkehr Alb-Bodensee GmbH (RAB)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Heidelberg Pre Waypoint to Milan
- Ave. Duration
- 8h 56m
- Frequency
- 3 times a day
- Estimated price
- €50–80
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Palermo
- Ave. Duration
- 21h 55m
- Frequency
- Twice daily
- Estimated price
- €140–210
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- €18–27
- Website
- Flixbus
Bus from Heidelberg Post Waypoint to Stuttgart Airport Busterminal
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- €11–18
- Website
- Flixbus
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
- Phone
- +49 (0) 6543 5019-400
- [email protected]
- Website
- Bohr
Bus from Mainz, Hauptbahnhof to Hahn
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €14–16
- Schedules at
- Bohr
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Stuttgart Airport to Palermo Piazza Cairoli
- Ave. Duration
- 29h 6m
- Frequency
- Once a week
- Estimated price
- €240–330
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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Booking & Getting There
Heidelberg to Palermo bus services, operated by FlixBus, arrive at Milan station.
Heidelberg to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Book your Heidelberg to Palermo train tickets online with Omio.
Book your Heidelberg to Palermo bus tickets online with Omio, FlixBus and 12go.asia.
There are 6015+ hotels available in Palermo.

















































