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How to get fromHeidelberg to Sienaby train, plane, train (Trenitalia), bus, night train, or car

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There are 12 ways to get from Heidelberg to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly to Florence Peretola Airport, train

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 13m
    €144–362

  2. Bus

    cheapest
    1. Take the bus from Mannheim central bus station to Florence Villa Constanza Bus Stationbus bus N77
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    19h 10m
    €90–158

  3. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h
    €120–680

  4. Bus via Karlsruhe

    1. Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus bus 198 / ...
    2. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    14h 49m

  5. Train, night train

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train 55 / ...
    2. Take the night train from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 45m
    €103–277

  6. Train to Frankfurt, fly to Pisa International Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    6h 57m
    €128–321

  7. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 29m
    €126–337

  8. Train to Frankfurt, fly to Venice Marco Polo Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 11m
    €118–362

  9. Train, train to Munich International Airport, fly to Florence Peretola Airport

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train
    2. Take the train from Hauptbahnhof to München Hbftrain train
    3. Fly from Munich International Airport (MUC) to Florence Peretola Airport (FLR)plane plane MUC - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 34m
    €183–541

  10. Train to Frankfurt, fly to Fiumicino International Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane plane FRA - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 18m
    €103–317

  11. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 13m
    €177–579

  12. Drive 941.1 km

    1. Drive from Heidelberg to Sienacar car 941.1 km
    9h 11m
    €148–213

Heidelberg to Siena by train

Calendar76Weekly Trains
Duration13hAverage Duration
Ticket€120Cheapest Price
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Questions & Answers

Map of how to get from Heidelberg to Siena.ExpandLaunch map view
  • Distance: 910.3 km
  • Duration: 7h 13m

What companies run services between Heidelberg, Germany and Siena, Italy?

You can take a train from Heidelberg, Hauptbahnhof to Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h. Alternatively, you can take a bus from Heidelberg Post Waypoint to Siena via Karlsruhe Central Bus Station and Florence Villa Constanza Bus Station in around 14h 49m.

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