There are 10 ways to get from Hempstead to Syracuse by bus (Flixbus), train, car, plane, bus (Greyhound), subway, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via New York (Flixbus)
best- Take the bus from New York Midtown to Syracuse Bus Stationbus FlixBus 2685 / ...
7h 1m$53–95Bus
cheapest- Take the bus from Hempstead Bus Station to Port Authority Bus Terminalbus Greyhound US0250
- Take the bus from Port Authority Bus Terminal to Syracuse Bus Stationbus Greyhound US0205 / ...
7h 14m$43–166Train
- Take the train from New York Penn Station to Syracusetrain VIA Rail
7h 8m$82–254Drive 251.3 mi
- Drive from Hempstead to Syracusecar 251.3 mi
5h 40m$46–67Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport
- Take the train from Hempstead to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
4h 55m$90–576Train, subway to Laguardia Airport, fly to Syracuse Hancock International Airport
- Take the train from Hempstead to Jamaicatrain
- Take the subway from Sutphin Blvd-Archer Av-JFK Airport to Jackson Hts-Roosevelt Avsubway
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
5h 10m$104–670Fly John F. Kennedy International Airport to Rochester, train
- Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane JFK - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 33m$123–690Fly Laguardia Airport to Rochester, train
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
6h 1m$142–854Fly John F. Kennedy International Airport to Ithaca Tompkins Regional Airport, bus
- Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane JFK - ITH
- Take the bus from Ithaca to Syracuse Bus Stationbus
6h 46m$58–315Fly Laguardia Airport to Buffalo Niagara International Airport, bus
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus
7h 8m$125–702
Hempstead to Syracuse by train and bus (Flixbus)
Questions & Answers
The cheapest way to get from Hempstead to Syracuse is to drive which costs $45 - $70 and takes 5h 40m.
The fastest way to get from Hempstead to Syracuse is to train and fly which takes 4h 55m and costs $90 - $600.
No, there is no direct bus from Hempstead to Syracuse station. However, there are services departing from New York Midtown and arriving at Syracuse Bus Station via . The journey, including transfers, takes approximately 7h 1m.
No, there is no direct train from Hempstead to Syracuse. However, there are services departing from Mineola and arriving at Syracuse via New York Penn Station. The journey, including transfers, takes approximately 7h 8m.
The distance between Hempstead and Syracuse is 324 miles. The road distance is 252.8 miles.
The best way to get from Hempstead to Syracuse without a car is to bus via New York which takes 7h 1m and costs $50 - $95.
It takes approximately 7h 1m to get from Hempstead to Syracuse, including transfers.
Hempstead to Syracuse bus services, operated by Flixbus USA, depart from New York Midtown station.
Hempstead to Syracuse train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Hempstead to Syracuse is to bus via New York which takes 7h 1m and costs $50 - $95. Alternatively, you can train, which costs $80 - $260 and takes 7h 8m.
What companies run services between Hempstead, NY, USA and Syracuse, NY, USA?
Flixbus USA operates a bus from New York Midtown to Syracuse Bus Station hourly. Tickets cost $45–80 and the journey takes 5h 15m. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $75–240 and the journey takes 5h 33m.
- Website
- delta.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $75–550
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $95–650
Flights from John F. Kennedy International Airport to Rochester
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $70–480
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $95–650
Flights from John F. Kennedy International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–280
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–750
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $75–550
Flights from John F. Kennedy International Airport to Rochester
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $70–480
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 33m
- Frequency
- Once daily
- Estimated price
- $75–240
- Website
- VIA Rail
- Escape
- $75–190
- Business
- $110–230
- Business Plus
- $120–240
- Economy
- $85–190
- Economy Plus
- $95–200
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from Hempstead to Jamaica
- Ave. Duration
- 32 min
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $5–9
Train from Hempstead to Jamaica
- Ave. Duration
- 32 min
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $5–9
- Phone
- 877-690-5116
- Website
- MTA Homepage
Subway from Sutphin Blvd-Archer Av-JFK Airport to Jackson Hts-Roosevelt Av
- Ave. Duration
- 15 min
- Frequency
- Every 10 minutes
- Estimated price
- $3
- Schedules at
- MTA Schedules
- Website
- MTA Homepage
- Website
- MTA: World Cup 2026
- Adult
- $3
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Hourly
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 6 times a week
- Estimated price
- $9–17
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 2 hours
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Hempstead Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $3–7
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 2 hours
- Estimated price
- $35–75
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Saver
- $40–150
- Flexible
- $70–160
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Hempstead to Syracuse bus services, operated by Flixbus USA, arrive at Syracuse Bus Station.
Hempstead to Syracuse train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Hempstead to Syracuse is 253 miles. It takes approximately 5h 40m to drive from Hempstead to Syracuse.
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