There are 8 ways to get from Henderson to Chicago by plane, bus, train, car, bus (Amtrak, Greyhound), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Mc Kellar-Sipes Regional Airport
best- Fly from Mc Kellar-Sipes Regional Airport (MKL) to Chicago O'Hare International Airport (ORD)plane MKL - ORD
3h$165–326Drive to Barkley Regional Airport, fly
cheapest- Drive from Henderson to Barkley Regional Airport (PAH)car
- Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane PAH - ORD
5h 13m$65–298Bus, train
- Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus
- Take the bus from Tornado Bus Co - West Memphis to Anna - Shellbus
- Take the train from Carbondale to Chicago Union Stationtrain
13h 9m$301–637Drive 497.1 mi
- Drive from Henderson to Chicagocar 497.1 mi
8h 47m$91–131Bus
- Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus Indianapolis
- Take the bus from Tornado Bus Co - West Memphis to Chicagobus Querétaro / ...
13h 11m$201–430Bus via Indianapolis
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus Memphis
- Take the bus from Indianapolis Union Station to Chicago Union Stationbus
14h 17m$171–329Bus via Bartlett
- Take the bus from Jackson to Memphis - Summer Avebus Nyc
- Take the bus from Memphis Bus Station to Chicago Bus Stationbus Greyhound US0125
15h 21m$172–278Bus, train via Indianapolis
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus Memphis
- Take the train from Indianapolis to Chicago Union Stationtrain Cardinal
15h 37m$203–404
Mc Kellar-Sipes Regional Airport (MKL) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Henderson to Chicago is to drive which costs $90 - $140 and takes 8h 47m.
The fastest way to get from Henderson to Chicago is to fly which takes 3h and costs $160 - $330.
No, there is no direct bus from Henderson to Chicago station. However, there are services departing from El Mezcal Grocery - Jackson, TN and arriving at Sox-35th Red Line Station via Tornado Bus Co - West Memphis and California & 35th Street. The journey, including transfers, takes approximately 13h 11m.
The distance between Henderson and Chicago is 488 miles. The road distance is 500 miles.
The best way to get from Henderson to Chicago without a car is to bus and train which takes 13h 9m and costs $300 - $650.
It takes approximately 3h to get from Henderson to Chicago, including transfers.
Henderson to Chicago bus services, operated by Tornado Bus Company, depart from El Mezcal Grocery - Jackson, TN station.
The best way to get from Henderson to Chicago is to fly which takes 3h and costs $160 - $330. Alternatively, you can bus, which costs $200 - $430 and takes 13h 11m.
Henderson to Chicago bus services, operated by Tornado Bus Company, arrive at Tornado Bus Co - West Memphis station.
Yes, the driving distance between Henderson to Chicago is 500 miles. It takes approximately 8h 47m to drive from Henderson to Chicago.
What companies run services between Henderson, TN, USA and Chicago, IL, USA?
Key Lime flies from Mc Kellar-Sipes Regional Airport (MKL) to Chicago O'Hare International Airport (ORD) 6 times a week. Alternatively, you can take a vehicle from Henderson to Harrison via El Mezcal Grocery - Jackson, TN, Tornado Bus Co - West Memphis, California & 35th Street, Sox-35th Red Line Station, and Sox-35th in around 13h 11m.
- Website
- keylimeair.com
Flights from Mc Kellar-Sipes Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–240
- Website
- united.com
Flights from Barkley Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Carbondale to Chicago Union Station
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphis
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a week
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Tornado Bus Co - West Memphis to Anna - Shell
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $50–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $50–150
Bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphis
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a week
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Tornado Bus Co - West Memphis to Chicago
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $95–210
- Schedules at
- tornadobus.com
- Adults 11-59
- $95–210
Bus from El Mezcal Grocery - Jackson, TN to Indianapolis
- Ave. Duration
- 7h 56m
- Frequency
- 3 times a week
- Estimated price
- $80–200
- Schedules at
- tornadobus.com
- Adults 11-59
- $80–200
Bus from El Mezcal Grocery - Jackson, TN to Indianapolis
- Ave. Duration
- 7h 56m
- Frequency
- 3 times a week
- Estimated price
- $80–200
- Schedules at
- tornadobus.com
- Adults 11-59
- $80–200
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Chicago Union Station
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $35–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $35–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Indianapolis Union Station to Chicago Union Station
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Jackson to Memphis - Summer Ave
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $30–45
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Memphis Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Once daily
- Estimated price
- $85–150
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 1328+ hotels available in Chicago.









