Rome2Rio

How to get fromHenderson to Santa Cruzby bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, subway, or bus (Amtrak)

Find Transport to Santa Cruz

See all options

There are 9 ways to get from Henderson to Santa Cruz by bus, plane, bus (Flixbus, Greyhound, Amtrak), train, car, subway, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 217 bus, fly to Norman Y. Mineta San José International Airport, bus

    best
    1. Take the bus from WB Lake Mead after Boulder to South Strip Transit Terminalbus bus
    2. Fly from Harry Reid International Airport (LAS) to Norman Y. Mineta San José International Airport (SJC)plane plane LAS - SJC
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    5h 17m
    $214–402

  2. Drive 522.1 mi

    cheapest
    1. Drive from Henderson to Santa Cruzcar car 522.1 mi
    9h 1m
    $96–138

  3. Bus

    1. Take the bus from Las Vegas Downtown to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to San Jose Diridon Stationbus bus
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    16h 11m
    $104–194

  4. Bus, train

    1. Take the bus from Las Vegas Downtown to Los Angeles Union Station Arrivalsbus bus
    2. Take the train from Los Angeles to San Josetrain train
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    19h 36m
    $184–374

  5. Fly to Oakland International Airport, BART, bus

    1. Fly from Harry Reid International Airport (LAS) to Oakland International Airport (OAK)plane plane LAS - OAK
    2. Take the subway from Coliseum to Berryessa / North San Josesubway subway
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    6h 4m
    $208–530

  6. Fly to San Francisco International Airport, Caltrain, bus

    1. Fly from Harry Reid International Airport (LAS) to San Francisco International Airport (SFO)plane plane LAS - SFO
    2. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    5h 58m
    $143–794

  7. Bus, train via Victorville

    1. Take the bus from SB Las Vegas at Fashion Show Mall to Victorville Transit Centerbus bus
    2. Take the train from Victorville Amtrak to Los Angelestrain train
    3. Take the train from Los Angeles to San Josetrain train
    4. Take the bus from Diridon Station to Ocean & Waterbus bus 17
    19h 58m
    $263–476

  8. Bus, train via Salinas

    1. Take the bus from Las Vegas Downtown to Los Angeles Downtownbus bus FlixBus 2030
    2. Take the train from Los Angeles to Salinastrain train Coast Starlight
    20h 10m
    $158–330

  9. Bus via Santa Barbara (Amtrak)

    1. Take the bus from South Strip Transit Terminal to Santa Barbarabus bus Amtrak Thruway Connecting Service
    2. Take the bus from Santa Barbara to Salinasbus bus Amtrak Thruway Connecting Service
    21h 51m
    $223–345

Henderson to Santa Cruz by bus

Calendar2Weekly Buses
Duration16h 11mAverage Duration
Ticket$104Cheapest Price
See schedules

Questions & Answers

Map of how to get from Henderson to Santa Cruz.ExpandLaunch map view
  • Distance: 440.2 mi
  • Duration: 5h 17m

What companies run services between Henderson, NV, USA and Santa Cruz, CA, USA?

You can take a bus from NB Boulder after Lake Mead to Soquel Ave & Front via Bonneville Transit Center Bay 14, Las Vegas Downtown, Los Angeles Union Station, San Jose Diridon Station, and Diridon Station in around 16h 11m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound