There are 5 ways to get from Highland to St. Louis by train (Amtrak), bus (Flixbus), car, taxi, train, plane, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
7h$130–243Drive 292.1 mi
cheapest- Drive from Highland to St. Louiscar 292.1 mi
4h 57m$54–77Bus (Flixbus)
- Take the bus from Chicago to St Louis Bus Stationbus FlixBus N2521
7h 44m$74–116Taxi, train to Chicago O'Hare International Airport, fly
- Take the taxi from Highland to East Chicagotaxi
- Take the train from East Chicago to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
4h 54m$317–758Taxi, train, subway to Chicago Midway International Airport, fly
- Take the taxi from Highland to East Chicagotaxi
- Take the train from East Chicago to Museum Campus/11th Street Sationtrain
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
4h 33m$122–608
Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Highland to St. Louis is to drive which costs $50 - $80 and takes 4h 57m.
The fastest way to get from Highland to St. Louis is to taxi and train and subway and fly which takes 4h 33m and costs $120 - $650.
No, there is no direct bus from Highland to St. Louis station. However, there are services departing from Ring Rd & Victory Center and arriving at St Louis Bus Station via Chicago. The journey, including transfers, takes approximately 7h 44m.
No, there is no direct train from Highland to St. Louis. However, there are services departing from East Chicago and arriving at St. Louis via Chicago Union Station. The journey, including transfers, takes approximately 7h.
The distance between Highland and St. Louis is 318 miles. The road distance is 293.8 miles.
The best way to get from Highland to St. Louis without a car is to train which takes 7h and costs $130 - $250.
It takes approximately 7h to get from Highland to St. Louis, including transfers.
Highland to St. Louis bus services, operated by Flixbus USA, depart from Chicago station.
Highland to St. Louis train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Highland to St. Louis is to train which takes 7h and costs $130 - $250. Alternatively, you can bus, which costs $70 - $120 and takes 7h 44m.
What companies run services between Highland, Lake County, IN, USA and St. Louis, MO, USA?
Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $85–190 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago to St Louis Bus Station once daily. Tickets cost $45–80 and the journey takes 5h 40m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $75–550
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $60–410
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $60–410
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $85–190
- Website
- Amtrak
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from East Chicago to Van Buren St.
- Ave. Duration
- 42 min
- Frequency
- Every 30 minutes
- Estimated price
- $6–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $6–8
Train from East Chicago to Museum Campus/11th Street Sation
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- $6–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $6–8
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago to St Louis Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
- Ave. Duration
- 17 min
- Estimated price
- $35–45
Krazy Cab of NWI
- Phone
- +1 219-763-1675
- Website
- krazycab.com
Krazy Cab of NWI
- Phone
- +1 219-763-1675
- Website
- krazycab.com
Want to know more about travelling around United States
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More Questions & Answers
Highland to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Highland to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Yes, the driving distance between Highland to St. Louis is 294 miles. It takes approximately 4h 57m to drive from Highland to St. Louis.
There are 482+ hotels available in St. Louis.











