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How to get fromHilton Head Island to Key Westby plane, taxi, train, shuttle, bus, or car

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There are 7 ways to get from Hilton Head Island to Key West by plane, taxi, train, shuttle, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Hilton Head Airport

    best
    1. Fly from Hilton Head Airport (HHH) to Key West International Airport (EYW)plane plane HHH - EYW
    5h 5m
    $86–341

  2. Taxi, train, shuttle

    1. Take the taxi from Hilton Head Island to Savannah Stationtaxi taxi
    2. Take the train from Savannah Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    20h 16m
    $634–880

  3. Taxi, train, bus via Jacksonville

    1. Take the taxi from Hilton Head Island to Savannah Stationtaxi taxi
    2. Take the train from Savannah Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    21h 32m
    $332–483

  4. Drive  676.8 mi

    1. Drive from Hilton Head Island to Key Westcar car 676.8 mi
    12h 12m
    $124–179

  5. Taxi to Savannah, fly

    1. Take the taxi from Hilton Head Island to Savannah (SAV)taxi taxi
    2. Fly from Savannah (SAV) to Key West International Airport (EYW)plane plane SAV - EYW
    4h 51m
    $226–542

  6. Drive to Brunswick Golden Isles Airport, fly

    1. Drive from Hilton Head Island to Brunswick Golden Isles Airport (BQK)car car
    2. Fly from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW)plane plane BQK - EYW
    6h 27m
    $91–352

  7. Taxi, train, bus

    1. Take the taxi from Hilton Head Island to Savannah Stationtaxi taxi
    2. Take the train from Savannah Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    20h 33m
    $489–696

Hilton Head Airport (HHH) to Key West International Airport (EYW) flights

Calendar19Weekly Planes
Duration6h 27mAverage Duration
Ticket$61Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hilton Head Island to Key West.ExpandLaunch map view
  • Distance: 539.7 mi
  • Duration: 5h 5m

What companies run services between Hilton Head Island, SC, USA and Key West, FL, USA?

Delta and American Airlines fly from Hilton Head Airport (HHH) to Key West International Airport (EYW) 3 times a day.

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