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How to get fromHilton Head Island to Knoxvilleby plane, taxi, train, bus, shuttle, or car

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There are 4 ways to get from Hilton Head Island to Knoxville by plane, taxi, train, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Hilton Head Airport

    best
    1. Fly from Hilton Head Airport (HHH) to Mcghee Tyson Airport (TYS)plane plane HHH - TYS
    3h 41m
    $165–688

  2. Drive 416.4 mi

    cheapest
    1. Drive from Hilton Head Island to Knoxvillecar car 416.4 mi
    7h 14m
    $76–110

  3. Taxi, train, bus, shuttle, drive

    1. Take the taxi from Hilton Head Island to Savannah Stationtaxi taxi
    2. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    5. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    19h 9m
    $586–738

  4. Taxi to Savannah, fly

    1. Take the taxi from Hilton Head Island to Savannah (SAV)taxi taxi
    2. Fly from Savannah (SAV) to Mcghee Tyson Airport (TYS)plane plane SAV - TYS
    4h 19m
    $335–1,059

Hilton Head Airport (HHH) to Mcghee Tyson Airport (TYS) flights

Calendar50Weekly Planes
Duration4h 52mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Hilton Head Island to Knoxville.ExpandLaunch map view
  • Distance: 328.1 mi
  • Duration: 3h 41m

What companies run services between Hilton Head Island, SC, USA and Knoxville, TN, USA?

Delta, American Airlines, and United Airlines fly from Hilton Head Airport (HHH) to Mcghee Tyson Airport (TYS) every 4 hours.

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