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How to get fromHolguín to Cayo Santa Maríaby bus, train, car, or plane

Find Transport to Cayo Santa María

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There are 5 ways to get from Holguín to Cayo Santa María by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Holguín to Santa Clarabus bus Holguin
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    10h 30m
    $11–23

  2. Train, bus

    1. Take the train from Holguin to Santa Claratrain train 16
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    13h 54m
    $11–25

  3. Drive 469.9 km

    1. Drive from Holguín to Cayo Santa Maríacar car 469.9 km
    7h 15m
    $54–77

  4. Fly, bus

    1. Fly from Frank País International Airport (HOG) to Abel Santamaría Airport (SNU)plane plane HOG - SNU
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    26h 23m
    $103–427

  5. Bus via Holguin

    1. Take the bus from Holguin to Santa Clarabus bus La Habana Vía Holguín / ...
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    11h 25m
    $42–64

Frank País International Airport (HOG) to Abel Santamaría Airport (SNU) flights

Calendar7Weekly Planes
Duration22h 45mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Holguín to Cayo Santa María.ExpandLaunch map view
  • Distance: 583.6 km
  • Duration: 10h 30m

What companies run services between Holguín, Cuba and Cayo Santa María, Villa Clara, Cuba?

You can take a bus from Holguín to Cayo Santa María via Parque, Vc, and Santa Clara in around 10h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Why you should take the train in the US, How to get from Heathrow Airport into central London, and Italian Lakes: Getting around by train - to help you get the most out of your next trip.