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How to get fromHolguín to Cayo Guillermoby bus, taxi, train, car, or plane

Find Transport to Cayo Guillermo

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There are 6 ways to get from Holguín to Cayo Guillermo by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Holguin to Ciego de Avilabus bus La Habana Vía Camaguey / ...
    2. Take the taxi from Morón to Cayo Guillermotaxi taxi
    8h 19m
    $89–113
  2. Drive  374.9 km

    cheapest
    1. Drive from Holguín to Cayo Guillermocar car 374.9 km
    5h 40m
    $43–62
  3. Train, taxi via Ciego de Ávila

    1. Take the train from Holguin to Ciego de Ávilatrain train 16
    2. Take the taxi from Morón to Cayo Guillermotaxi taxi
    9h 53m
    $68–86
  4. Fly, train, taxi

    1. Fly from Frank País International Airport (HOG) to Ignacio Agramonte International Airport (CMW)plane plane HOG - CMW
    2. Take the train from Camagüey to Moróntrain train
    3. Take the taxi from Morón to Cayo Guillermotaxi taxi
    31h 1m
    $149–503
  5. Train, taxi

    1. Take the train from Holguin to Ciego de Ávilatrain train 16
    2. Take the taxi from Morón to Cayo Guillermotaxi taxi
    10h 22m
    $68–86
  6. Bus, taxi via Camagüey

    1. Take the bus from Holguin to Camagüeybus bus
    2. Take the bus from Camaguey to Chambasbus bus
    3. Take the taxi from Chambas to Cayo Guillermotaxi taxi
    10h 38m
    $108–136

Frank País International Airport (HOG) to Ignacio Agramonte International Airport (CMW) flights

Calendar5Weekly Planes
Duration22h 40mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

What companies run services between Holguín, Cuba and Cayo Guillermo, Cuba?

There is no direct connection from Holguín to Cayo Guillermo. However, you can take the bus to Ciego de Avila, walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo. Alternatively, you can take the train to Ciego de Ávila, walk to Ciego de Ávila, take the bus to Morón, then take the taxi to Cayo Guillermo.

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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from JFK to New York City, Travelling to the US: What do I need to know?, and What are the different types of Renfe trains in Spain? - to help you get the most out of your next trip.