There are 3 ways to get from Holguín to Santiago by plane or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Frank País International Airport
best- Fly from Frank País International Airport (HOG) to Comodoro Arturo Merino Benítez International Airport (SCL)plane HOG - SCL
14h 41m$227–861Shuttle to Ignacio Agramonte International Airport, fly
- Take a shuttle bus from Hotel Pernik Holguin to Hotel Camagüey
- Fly from Ignacio Agramonte International Airport (CMW) to Comodoro Arturo Merino Benítez International Airport (SCL)plane CMW - SCL
17h 1m$256–955Shuttle to Antonio Maceo International Airport, fly
- Take a shuttle bus from Hotel Pernik Holguin to Melia Santiago de Cuba
- Fly from Antonio Maceo International Airport (SCU) to Comodoro Arturo Merino Benítez International Airport (SCL)plane SCU - SCL
21h$254–934
Frank País International Airport (HOG) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Comparing Your Travel Options
The cheapest way to get from Holguín to Santiago is to fly which costs $220 - $900 and takes 14h 41m.
The fastest way to get from Holguín to Santiago is to fly which takes 14h 41m and costs $220 - $900.
The distance between Holguín and Santiago is 6079 km.
It takes approximately 14h 41m to get from Holguín to Santiago, including transfers.
Santiago is 1h ahead of Holguín. It is currently 8:36 PM in Holguín and 9:36 PM in Santiago.
There are 3316+ hotels available in Santiago.
What companies run services between Holguín, Cuba and Santiago, Chile?
American Airlines and LATAM Chile fly from Frank País International Airport (HOG) to Comodoro Arturo Merino Benítez International Airport (SCL) once daily.
- Website
- latam.com
Flights from Frank País International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 12h 20m
- When
- Tuesday to Wednesday
- Estimated price
- $340–1,000
Flights from Ignacio Agramonte International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 12h 25m
- When
- Tuesday to Wednesday
- Estimated price
- $330–950
Flights from Ignacio Agramonte International Airport to Comodoro Arturo Merino Benítez International Airport via Miami, Lima
- Ave. Duration
- 14h
- When
- Every day
- Estimated price
- $210–850
Flights from Antonio Maceo International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 16h 20m
- When
- Monday
- Estimated price
- $340–1,000
- Website
- aa.com
Flights from Frank País International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 15h 45m
- When
- Every day
- Estimated price
- $220–850
Flights from Ignacio Agramonte International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 15h 50m
- When
- Every day
- Estimated price
- $210–850
Flights from Antonio Maceo International Airport to Comodoro Arturo Merino Benítez International Airport via Miami
- Ave. Duration
- 19h 30m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $220–850
- Website
- avianca.com
Flights from Antonio Maceo International Airport to Comodoro Arturo Merino Benítez International Airport via Santo Domingo, Bogota
- Ave. Duration
- 17h 45m
- When
- Monday
- Estimated price
- $360–1,100
- Phone
- +(537) 206 9590
- [email protected]
- Website
- ecured.cu
Shuttle from Hotel Pernik Holguin to Hotel Camagüey
- Ave. Duration
- 1h 59m
- Frequency
- Twice daily
- Estimated price
- $40–100
- Schedules at
- viajescubanacan.cu
Shuttle from Hotel Pernik Holguin to Melia Santiago de Cuba
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- $28–80
- Schedules at
- viajescubanacan.cu
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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Heading to Europe? Read this before you buy a Eurail Pass, Which London airport should I choose?, and How to get from Luton Airport into central London - to help you get the most out of your next trip.



