Rome2Rio

How to get fromHolliston to Ithacaby bus (Greyhound, Flixbus), train, bus, car, or plane

Find Transport to Ithaca

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 7 ways to get from Holliston to Ithaca by bus (Greyhound, Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Framingham to Springfield Union Stationbus bus Greyhound US0270s
    2. Take the bus from Springfield Union Station to Ithacabus bus FlixBus 2691
    9h 43m
    $60–92

  2. Drive  314 mi

    cheapest
    1. Drive from Holliston to Ithacacar car 314 mi
    5h 54m
    $54–78

  3. Train, bus

    1. Take the train from Framingham Amtrak to Utica Amtrak Stationtrain train Lake Shore Limited
    2. Take the bus from Utica Bus Stop to Ithacabus bus FlixBus 2691
    11h 48m
    $170–268

  4. Fly to Ithaca Tompkins Regional Airport

    1. Fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH)plane plane BOS - ITH
    8h 34m
    $74–410

  5. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the bus from Rochester to Ithacabus bus
    8h 6m
    $112–480

  6. Train, fly to Syracuse Hancock International Airport, bus

    1. Take the train from Framingham to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    8h 4m
    $82–432

  7. Fly to Buffalo Niagara International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    2. Take the bus from Buffalo Niagara International Airport to Ithacabus bus
    9h 25m
    $138–710

Holliston to Ithaca by bus

Calendar3Weekly Buses
Duration9h 43mAverage Duration
Ticket$60Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Holliston to Ithaca.ExpandLaunch map view
  • Distance: 371.2 mi
  • Duration: 9h 43m

What companies run services between Holliston, MA, USA and Ithaca, NY, USA?

You can take a bus from Downtown Holliston to Ithaca via Framingham MBTA Station, Framingham, and Springfield Union Station in around 9h 43m. Alternatively, United Airlines, Delta, and JetBlue Airways fly from Boston Logan Airport (BOS) to Ithaca Tompkins Regional Airport (ITH) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There