Rome2Rio

How to get fromHolliston to Syracuseby bus (Greyhound, Flixbus), train (Amtrak), car, train, or plane

Find Transport to Syracuse

See all options

There are 5 ways to get from Holliston to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Framingham to Springfield Union Stationbus bus Greyhound US0270s
    2. Take the bus from Springfield Union Station to Syracuse Bus Stationbus bus Greyhound US0171 / ...
    8h 32m
    $42–88

  2. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    9h 43m
    $102–222

  3. Drive 293.1 mi

    1. Drive from Holliston to Syracusecar car 293.1 mi
    5h 12m
    $54–78

  4. Train, fly to Syracuse Hancock International Airport

    1. Take the train from Framingham to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    6h 28m
    $94–578

  5. Fly to Rochester, train

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 25m
    $138–812

Holliston to Syracuse by bus

Calendar2Weekly Buses
Duration8h 32mAverage Duration
Ticket$42Cheapest Price
See schedules

Questions & Answers

Map of how to get from Holliston to Syracuse.ExpandLaunch map view
  • Distance: 308.3 mi
  • Duration: 8h 32m

What companies run services between Holliston, MA, USA and Syracuse, NY, USA?

You can take a bus from Downtown Holliston to Syracuse Bus Station via Framingham MBTA Station, Framingham, and Springfield Union Station in around 8h 32m. Alternatively, Amtrak operates a train from Framingham Amtrak to Syracuse Regional Transportation Center once daily. Tickets cost $100–220 and the journey takes 8h 26m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers