There are 12 ways to get from Homosassa to Florida Keys by taxi, shuttle, plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, shuttle to Tampa, fly to Key West International Airport
best- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
6h 54m$255–579Drive 427.8 mi
cheapest- Drive from Homosassa to Florida Keyscar 427.8 mi
8h 55m$79–113Drive, train, bus
- Drive from Homosassa to Tampacar
- Take the train from Tampa to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
13h 9m$116–231Taxi, shuttle to Orlando, fly to Key West International Airport
- Take the taxi from Homosassa to Sleep Inn and Suites Wildwood-The Villagestaxi
- Take a shuttle bus from Sleep Inn and Suites Wildwood-The Villages to Orlando Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
7h 22m$334–961Taxi, shuttle to Tampa, fly to Miami International Airport, shuttle
- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 24m$925–1,439Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Homosassa to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
6h 22m$129–358Taxi, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport, bus
- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
8h 52m$236–485Taxi, shuttle to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 53m$395–909Taxi, bus
- Take the taxi from Homosassa to Ocala, FLtaxi
- Take the bus from Ocala, FL to Miami Airportbus
- Take the bus from Miami Airport Station to Big Pine Keybus
13h 20m$224–338Taxi, bus via Orlando
- Take the taxi from Homosassa to Ocala, FLtaxi
- Take the bus from Ocala, FL to Orlando - RedCoach Station, FLbus
- Take the bus from Orlando to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
14h 21m$202–285Taxi, shuttle, bus via Fort Lauderdale Airport (FLL)
- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Take the bus from Tampa Bus Station to Fort Lauderdale International Airportbus
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Lab
15h 27m$332–422Taxi, shuttle, bus
- Take the taxi from Homosassa to Brooksville Wawataxi
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Take the bus from Tampa Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
16h 9m$185–277
Tampa (TPA) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Homosassa to Florida Keys is to drive which costs $75 - $120 and takes 8h 55m.
The fastest way to get from Homosassa to Florida Keys is to drive and fly which takes 6h 22m and costs $120 - $360.
The distance between Homosassa and Florida Keys is 351 miles. The road distance is 430.3 miles.
The best way to get from Homosassa to Florida Keys without a car is to taxi and bus which takes 13h 20m and costs $220 - $340.
It takes approximately 6h 54m to get from Homosassa to Florida Keys, including transfers.
Yes, the driving distance between Homosassa to Florida Keys is 430 miles. It takes approximately 8h 55m to drive from Homosassa to Florida Keys.
There are 972+ hotels available in Florida Keys.
What companies run services between Homosassa, FL, USA and Florida Keys, FL, USA?
There is no direct connection from Homosassa to Florida Keys. However, you can take the taxi to Brooksville Wawa, take the shuttle to Tampa International Airport - Red Terminal, walk to Tampa (TPA) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take a vehicle from Homosassa to Florida Keys via Tampa, Miami Amtrak Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 13h 9m.
- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $35–250
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $30–230
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $40–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Miami Amtrak Station
- Ave. Duration
- 5h 26m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- Amtrak
- Phone
- +1 352 539 9664
- Website
- Groome Transportation
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- Groome Transportation
- online discount
- $35–45
- call in
- $40–50
- Ave. Duration
- 41 min
- Estimated price
- $85–160
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