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How to get fromHonolulu to Mayo Clinicby plane, bus, or car

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There are 3 ways to get from Honolulu to Mayo Clinic by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Daniel K. Inouye International Airport (HNL) to Rochester (RST)plane plane HNL - RST
    15h 56m
    $244–943

  2. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Daniel K. Inouye International Airport (HNL) to Minneapolis–Saint Paul International Airport (MSP)plane plane HNL - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    12h 21m
    $353–1,153

  3. Fly to Fort Dodge Municipal Airport, drive

    1. Fly from Daniel K. Inouye International Airport (HNL) to Fort Dodge Municipal Airport (FOD)plane plane HNL - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Mayo Cliniccar car
    14h 51m
    $273–953

Daniel K. Inouye International Airport (HNL) to Rochester (RST) flights

Calendar29Weekly Planes
Duration14h 14mAverage Duration
Ticket$246Cheapest Price
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Comparing Your Travel Options

Map of how to get from Honolulu to Mayo Clinic.ExpandLaunch map view
  • Distance: 4,016.5 mi
  • Duration: 15h 56m

What companies run services between Honolulu, HI, USA and Mayo Clinic, MN, USA?

American Airlines, Delta, and United Airlines fly from Daniel K. Inouye International Airport (HNL) to Rochester (RST) 4 times a day.

Airlines
Bus operators

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