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How to get fromHonolulu to Mayo Clinicby plane or bus

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There are 2 ways to get from Honolulu to Mayo Clinic by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Daniel K. Inouye International Airport (HNL) to Rochester (RST)plane plane HNL - RST
    13h 33m
    $353–1,303

  2. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Daniel K. Inouye International Airport (HNL) to Minneapolis–Saint Paul International Airport (MSP)plane plane HNL - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    11h 56m
    $475–1,455

Daniel K. Inouye International Airport (HNL) to Rochester (RST) flights

Calendar41Weekly Planes
Duration14h 5mAverage Duration
Ticket$358Cheapest Price
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Questions & Answers

Map of how to get from Honolulu to Mayo Clinic.ExpandLaunch map view
  • Distance: 4,016.5 mi
  • Duration: 13h 33m

What companies run services between Honolulu, HI, USA and Mayo Clinic, MN, USA?

American Airlines, United Airlines, and Delta fly from Daniel K. Inouye International Airport (HNL) to Rochester (RST) every 4 hours.

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