There are 5 ways to get from Hopkinton to Portland by train, bus, train (Amtrak), car, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Southborough to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston, MA - South Station to Portland, MEbus Logan Airport / ...
4h 15m$28–58Drive 135 mi
cheapest- Drive from Hopkinton to Portlandcar 135 mi
2h 20m$24–35Train
- Take the train from Southborough to Back Baytrain Framingham/Worcester Line
- Take the train from Boston to Portlandtrain Downeaster
5h 36m$68–116Bus
- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston, MA - South Station to Portland, MEbus Logan Airport / ...
4h 42m$26–52Train, bus via City of Portland
- Take the train from Southborough to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston to City of Portlandbus FlixBus N2615
5h 1m$24–42
Hopkinton to Portland by bus and train
Comparing Your Travel Options
The cheapest way to get from Hopkinton to Portland is to drive which costs $23 - $35 and takes 2h 20m.
The fastest way to get from Hopkinton to Portland is to drive which takes 2h 20m and costs $23 - $35.
No, there is no direct bus from Hopkinton to Portland. However, there are services departing from Hopkinton Center and arriving at Portland, ME via Framingham and Boston, MA - South Station. The journey, including transfers, takes approximately 4h 42m.
No, there is no direct train from Hopkinton to Portland. However, there are services departing from Southborough and arriving at Portland via Back Bay and Boston. The journey, including transfers, takes approximately 5h 36m.
The distance between Hopkinton and Portland is 137 miles. The road distance is 135.8 miles.
The best way to get from Hopkinton to Portland without a car is to train and bus which takes 4h 15m and costs $27 - $60.
It takes approximately 4h 15m to get from Hopkinton to Portland, including transfers.
Hopkinton to Portland bus services, operated by Greyhound USA, depart from Framingham station.
Hopkinton to Portland train services, operated by MBTA, depart from Southborough station.
The best way to get from Hopkinton to Portland is to train which takes 5h 36m and costs $65 - $120. Alternatively, you can bus, which costs $26 - $55 and takes 4h 42m.
What companies run services between Hopkinton, MA, USA and Portland, ME, USA?
You can take a bus from Hopkinton Center to Portland via Southborough MBTA Station, Southborough, Back Bay, Back Bay, North Station, and Boston in around 5h 36m. Alternatively, you can take a bus from Hopkinton Center to Portland, ME via Framingham MBTA Station, Framingham, Boston, and Boston, MA - South Station in around 4h 42m.
Train from Southborough to South Station
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Train from Southborough to Back Bay
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Southborough to South Station
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Portland
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $60–100
- Website
- Amtrak
- Phone
- +1 800 639 3317
- [email protected]
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- Greyhound
Bus from Boston to City of Portland
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $19–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to City of Portland
- Ave. Duration
- 2h
- Frequency
- 6 times a week
- Estimated price
- $17–26
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Hopkinton to Portland bus services, operated by Greyhound USA, arrive at Boston station.
Hopkinton to Portland train services, operated by MBTA, arrive at Back Bay station.
Yes, the driving distance between Hopkinton to Portland is 136 miles. It takes approximately 2h 20m to drive from Hopkinton to Portland.
There are 395+ hotels available in Portland.
















