There are 4 ways to get from Hopkinton to Portsmouth by train, bus, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Framingham to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston to Portsmouth Bus Stopbus FlixBus N2615
3h 59m$14–28Bus
cheapest- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston to Portsmouth Bus Stopbus FlixBus N2615
4h 15m$12–26Drive 85.5 mi
- Drive from Hopkinton to Portsmouthcar 85.5 mi
1h 32m$16–23Train, bus via Boston Airport (BOS)
- Take the train from Framingham to Back Baytrain Framingham/Worcester Line
- Take the bus from Boston to Portsmouthbus Cj00:40-Lgpm
5h 6m$28–48
Hopkinton to Portsmouth by bus and train
Questions & Answers
The cheapest way to get from Hopkinton to Portsmouth is to bus which costs $12 - $26 and takes 4h 15m.
The fastest way to get from Hopkinton to Portsmouth is to drive which takes 1h 32m and costs $15 - $23.
No, there is no direct bus from Hopkinton to Portsmouth. However, there are services departing from Hopkinton Center and arriving at Portsmouth Bus Stop via Framingham and Boston. The journey, including transfers, takes approximately 4h 15m.
The distance between Hopkinton and Portsmouth is 88 miles. The road distance is 86 miles.
The best way to get from Hopkinton to Portsmouth without a car is to train and bus which takes 3h 59m and costs $13 - $29.
It takes approximately 3h 59m to get from Hopkinton to Portsmouth, including transfers.
Hopkinton to Portsmouth bus services, operated by Greyhound USA, depart from Framingham station.
Hopkinton to Portsmouth bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Hopkinton to Portsmouth is 86 miles. It takes approximately 1h 32m to drive from Hopkinton to Portsmouth.
There are 378+ hotels available in Portsmouth.
What companies run services between Hopkinton, MA, USA and Portsmouth, NH, USA?
You can take a bus from Hopkinton Center to Portsmouth Bus Stop via Framingham MBTA Station, Framingham, and Boston in around 4h 15m.
Train from Framingham to South Station
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- $4–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–10
Train from Framingham to Back Bay
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $3–7
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Boston to Portsmouth
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Want to know more about travelling around United States
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