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How to get fromHopkinton to Syracuseby bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, plane, or bus (Flixbus)

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There are 6 ways to get from Hopkinton to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Framingham to Springfield Union Stationbus bus Greyhound US0270s
    2. Take the bus from Springfield Union Station to Syracuse Bus Stationbus bus Greyhound US0171 / ...
    8h 40m
    $42–88

  2. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    9h 51m
    $102–222

  3. Drive 286.8 mi

    1. Drive from Hopkinton to Syracusecar car 286.8 mi
    5h 1m
    $53–76

  4. Line 05 bus, train, fly to Syracuse Hancock International Airport

    1. Take the bus from Hopkinton Center to Framingham MBTA Stationbus bus
    2. Take the train from Framingham to Back Baytrain train
    3. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    6h 33m
    $100–578

  5. Bus via West Albany

    1. Take the bus from Worcester Union Station to Albany Bus Terminal, NYbus bus FlixBus 2693
    2. Take the bus from Albany to Syracusebus bus Adt A264
    10h 30m
    $50–128

  6. Fly to Rochester, train

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 31m
    $138–762

Hopkinton to Syracuse by bus

Calendar14Weekly Buses
Duration8h 40mAverage Duration
Ticket$42Cheapest Price
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Questions & Answers

Map of how to get from Hopkinton to Syracuse.ExpandLaunch map view
  • Distance: 311.5 mi
  • Duration: 8h 40m

What companies run services between Hopkinton, MA, USA and Syracuse, NY, USA?

You can take a bus from Hopkinton Center to Syracuse Bus Station via Framingham MBTA Station, Framingham, and Springfield Union Station in around 8h 40m. Alternatively, Amtrak operates a train from Framingham Amtrak to Syracuse Regional Transportation Center once daily. Tickets cost $100–220 and the journey takes 8h 26m.

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