There are 6 ways to get from Hot Springs to Mayo Clinic by taxi, plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, fly to Rochester
best- Take the taxi from Hot Springs to Bill And Hillary Clinton National Airport (LIT)taxi
- Fly from Bill And Hillary Clinton National Airport (LIT) to Rochester (RST)plane LIT - RST
6h 52m$206–608Drive 776.6 mi
cheapest- Drive from Hot Springs to Mayo Cliniccar 776.6 mi
15h 6m$133–192Taxi, bus
- Take the taxi from Hot Springs to Shell gas station - Little Rock, ARtaxi
- Take the bus from Shell gas station - Little Rock, AR to Water & Chicago - Circle Kbus
- Take the bus from Milwaukee to Rochesterbus
21h 51m$321–389Train, bus via Madison
- Take the train from Malvern Station to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
25h 36m$484–787Taxi, fly to Minneapolis–Saint Paul International Airport, bus
- Take the taxi from Hot Springs to Bill And Hillary Clinton National Airport (LIT)taxi
- Fly from Bill And Hillary Clinton National Airport (LIT) to Minneapolis–Saint Paul International Airport (MSP)plane LIT - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 51m$275–748Train, bus
- Take the train from Malvern Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochesterbus
26h 55m$657–1,047
Bill And Hillary Clinton National Airport (LIT) to Rochester (RST) flights
Comparing Your Travel Options
The cheapest way to get from Hot Springs to Mayo Clinic is to drive which costs $130 - $200 and takes 15h 6m.
The fastest way to get from Hot Springs to Mayo Clinic is to taxi and fly which takes 6h 52m and costs $200 - $650.
The distance between Hot Springs and Mayo Clinic is 704 miles. The road distance is 781.2 miles.
The best way to get from Hot Springs to Mayo Clinic without a car is to taxi and bus which takes 21h 51m and costs $320 - $390.
It takes approximately 6h 52m to get from Hot Springs to Mayo Clinic, including transfers.
Yes, the driving distance between Hot Springs to Mayo Clinic is 781 miles. It takes approximately 15h 6m to drive from Hot Springs to Mayo Clinic.
There are 76+ hotels available in Mayo Clinic.
What companies run services between Hot Springs, AR, USA and Mayo Clinic, MN, USA?
There is no direct connection from Hot Springs to Mayo Clinic. However, you can take the taxi to Bill And Hillary Clinton National Airport (LIT) airport, fly to Rochester (RST), walk to Rochester, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can take the taxi to Shell gas station - Little Rock, AR, take the bus to Water & Chicago - Circle K, walk to Milwaukee, take the bus to Rochester, then walk to Mayo Clinic.
- Website
- aa.com
Flights from Bill And Hillary Clinton National Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $80–420
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $120–600
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Bill And Hillary Clinton National Airport to Rochester via Atlanta, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 8h 10m
- When
- Every day
- Estimated price
- $110–550
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Atlanta
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $140–650
- Website
- united.com
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Chicago O'Hare
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $100–550
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Dallas
- Ave. Duration
- 6h 10m
- When
- Sunday
- Estimated price
- $120–600
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Nashville
- Ave. Duration
- 6h 27m
- When
- Saturday, Monday, and Thursday
- Estimated price
- $110–600
Flights from Bill And Hillary Clinton National Airport to Minneapolis–Saint Paul International Airport via Denver
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Malvern Station to Chicago Union Station
- Ave. Duration
- 15h 23m
- Frequency
- Once daily
- Estimated price
- $360–600
- Website
- Amtrak
Train from Malvern Station to Chicago Union Station
- Ave. Duration
- 15h 23m
- Frequency
- Once daily
- Estimated price
- $360–600
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Shell gas station - Little Rock, AR to Water & Chicago - Circle K
- Ave. Duration
- 14h 3m
- Frequency
- Once daily
- Estimated price
- $150–170
- Schedules at
- Tornado Bus Company
- Adult
- $150–170
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Ave. Duration
- 58 min
- Estimated price
- $100–150
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide

















