There are 5 ways to get from Houston to Florence by plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO)plane IAH - FLO
7h 43m$133–417Bus via Sandy Springs
- Take the bus from Houston - Harrisburg Blvd to Atlantabus Houston
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus Greyhound US0641S / ...
22h 50m$189–259Train (Amtrak)
- Take the train from Houston to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Greensborotrain
- Take the train from Greensboro to Selma Stationtrain
- Take the train from Selma Station to Florence Stationtrain
38h 44m$800–1,271Drive 1,075.9 mi
- Drive from Houston to Florencecar 1,075.9 mi
17h 34m$184–266Bus (Greyhound)
- Take the bus from Houston Bus Station to Atlanta Bus Stationbus Greyhound US0602
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus Greyhound US0641S / ...
25h 8m$206–317
Houston to Florence by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Houston to Florence is to bus via Sandy Springs which costs $180 - $260 and takes 22h 50m.
The fastest way to get from Houston to Florence is to fly which takes 7h 43m and costs $130 - $420.
No, there is no direct bus from Houston to Florence station. However, there are services departing from Houston - Harrisburg Blvd and arriving at Florence Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 22h 50m.
No, there is no direct train from Houston to Florence station. However, there are services departing from Houston and arriving at Florence Station via New Orleans Union Passenger Terminal, Greensboro and Selma Station. The journey, including transfers, takes approximately 38h 44m.
The distance between Houston and Florence is 990 miles. The road distance is 1082.2 miles.
The best way to get from Houston to Florence without a car is to bus via Sandy Springs which takes 22h 50m and costs $180 - $260.
It takes approximately 7h 43m to get from Houston to Florence, including transfers.
Houston to Florence bus services, operated by Omnibus Express, depart from Houston - Harrisburg Blvd station.
Houston to Florence train services, operated by Amtrak, depart from Houston station.
The best way to get from Houston to Florence is to fly which takes 7h 43m and costs $130 - $420. Alternatively, you can bus via Sandy Springs, which costs $180 - $260 and takes 22h 50m, you could also train, which costs $800 - $1,300 and takes 38h 44m.
What companies run services between Houston, TX, USA and Florence, SC, USA?
American Airlines and Frontier Airlines fly from George Bush Intercontinental Airport (IAH) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a vehicle from Central Station Rusk EB to Florence Bus Station via Magnolia Park Transit Center EB, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 22h 50m.
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $90–460
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Houston to New Orleans Union Passenger Terminal
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a week
- Estimated price
- $200–310
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Greensboro
- Ave. Duration
- 21h 12m
- Frequency
- Once daily
- Estimated price
- $470–750
- Website
- Amtrak
Train from Greensboro to Selma Station
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $60–95
- Website
- Amtrak
Train from Selma Station to Florence Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Amtrak
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Atlanta
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $130–170
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Houston Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 15m
- Frequency
- Every 4 hours
- Estimated price
- $150–230
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $55–85
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Houston to Florence bus services, operated by Omnibus Express, arrive at Atlanta station.
Florence is 1h ahead of Houston. It is currently 11:18 AM in Houston and 12:18 PM in Florence.
Houston to Florence train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between Houston to Florence is 1082 miles. It takes approximately 17h 34m to drive from Houston to Florence.
Book your Houston to Florence train tickets online with Omio.
Book your Houston to Florence bus tickets online with Omio.
There are 47+ hotels available in Florence.









