There are 8 ways to get from Houston to Florida Keys by plane, bus (Greyhound), car, shuttle, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly George Bush Intercontinental Airport to Key West International Airport
best- Fly from George Bush Intercontinental Airport (IAH) to Key West International Airport (EYW)plane IAH - EYW
9h 43m$160–478Bus
- Take the bus from Houston - Harrisburg Blvd to Miamibus Houston
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
31h 44m$212–295Drive 1,309.2 mi
- Drive from Houston to Florida Keyscar 1,309.2 mi
22h 45m$239–346Fly William P. Hobby Airport to Key West International Airport
- Fly from William P. Hobby Airport (HOU) to Key West International Airport (EYW)plane HOU - EYW
9h 41m$188–645Fly William P. Hobby Airport to Miami International Airport, shuttle
- Fly from William P. Hobby Airport (HOU) to Miami International Airport (MIA)plane HOU - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 21m$293–885Fly William P. Hobby Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from William P. Hobby Airport (HOU) to Fort Lauderdale–Hollywood International Airport (FLL)plane HOU - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 46m$653–1,305Fly George Bush Intercontinental Airport to Miami International Airport, shuttle
- Fly from George Bush Intercontinental Airport (IAH) to Miami International Airport (MIA)plane IAH - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 56m$255–888Bus via Tallahassee
- Take the bus from Houston Bus Station to Tallahasseebus
- Take the bus from Tallahassee to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
37h 8m$195–391
Houston to Florida Keys by bus and foot
Questions & Answers
The cheapest way to get from Houston to Florida Keys is to bus via Tallahassee which costs $190 - $400 and takes 37h 8m.
The fastest way to get from Houston to Florida Keys is to fly and shuttle which takes 9h 21m and costs $290 - $900.
No, there is no direct bus from Houston to Florida Keys. However, there are services departing from Houston - Harrisburg Blvd and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 31h 44m.
The distance between Houston and Florida Keys is 965 miles. The road distance is 1316.9 miles.
The best way to get from Houston to Florida Keys without a car is to bus which takes 31h 44m and costs $210 - $300.
It takes approximately 9h 43m to get from Houston to Florida Keys, including transfers.
Houston to Florida Keys bus services, operated by Omnibus Express, depart from Houston - Harrisburg Blvd station.
The best way to get from Houston to Florida Keys is to fly which takes 9h 43m and costs $160 - $480. Alternatively, you can bus, which costs $210 - $300 and takes 31h 44m.
Houston to Florida Keys bus services, operated by Omnibus Express, arrive at Miami station.
Yes, the driving distance between Houston to Florida Keys is 1317 miles. It takes approximately 22h 45m to drive from Houston to Florida Keys.
What companies run services between Houston, TX, USA and Florida Keys, FL, USA?
Delta and American Airlines fly from George Bush Intercontinental Airport (IAH) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a vehicle from Central Station Rusk EB to Florida Keys via Magnolia Park Transit Center EB, Houston - Harrisburg Blvd, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 31h 44m.
- Website
- southwest.com
Flights from William P. Hobby Airport to Miami International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $140–700
Flights from William P. Hobby Airport to Miami International Airport via Orlando
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $150–750
Flights from William P. Hobby Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $140–750
Flights from William P. Hobby Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 5h 11m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from William P. Hobby Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 5h 35m
- When
- Saturday
- Estimated price
- $150–750
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
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There are 972+ hotels available in Florida Keys.


