There are 11 ways to get from Houston to Kirksville by plane, bus, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly George Bush Intercontinental Airport to Kirksville Regional Airport
best- Fly from George Bush Intercontinental Airport (IAH) to Kirksville Regional Airport (IRK)plane IAH - IRK
6h 31m$127–583Bus, train via Oklahoma City
- Take the bus from Hyatt Regency Houston to Fort Worthbus
- Take the train from Fort Worth to Oklahoma Citytrain
- Take the bus from Oklahoma City to Newton Stationbus
- Take the train from Newton Station to La Plata Stationtrain
22h 20m$352–642Bus, train
- Take the bus from Downtown Houston to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Kansas City Bus Stationbus
- Take the train from Kansas City to La Plata Stationtrain
23h 7m$200–367Drive 884.9 mi
- Drive from Houston to Kirksvillecar 884.9 mi
15h 19m$162–234Fly William P. Hobby Airport to Kansas City, train
- Fly from William P. Hobby Airport (HOU) to Kansas City (MCI)plane HOU - MCI
- Take the train from Kansas City to La Plata Stationtrain
9h$211–951Fly George Bush Intercontinental Airport to Kansas City, train
- Fly from George Bush Intercontinental Airport (IAH) to Kansas City (MCI)plane IAH - MCI
- Take the train from Kansas City to La Plata Stationtrain
9h 34m$173–754Fly William P. Hobby Airport to Kirksville Regional Airport
- Fly from William P. Hobby Airport (HOU) to Kirksville Regional Airport (IRK)plane HOU - IRK
7h 3m$305–1,330Fly William P. Hobby Airport to Lambert–St. Louis International Airport, shuttle
- Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane HOU - STL
- Take a shuttle bus from St. Louis to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to Columbia
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
10h 44m$145–772Fly George Bush Intercontinental Airport to Lambert–St. Louis International Airport, shuttle
- Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane IAH - STL
- Take a shuttle bus from St. Louis to Bowling Green, Mo
- Take a shuttle bus from Bowling Green, Mo to Columbia
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
11h 22m$307–975Bus, train #2
- Take the bus from Houston Bus Station to Texarkanabus
- Take the bus from Texarkana to Kansas Citybus
- Take the train from Kansas City to La Plata Stationtrain
23h 39m$236–402Bus, train #3 (Amtrak)
- Take the bus from Houston to Longviewbus
- Take the train from Longview to Springfieldtrain
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Take the train from Galesburg Amtrak Station to La Plata Stationtrain
28h 5m$327–723
George Bush Intercontinental Airport (IAH) to Kirksville Regional Airport (IRK) flights
Comparing Your Travel Options
The cheapest way to get from Houston to Kirksville is to drive which costs $160 - $240 and takes 15h 19m.
The fastest way to get from Houston to Kirksville is to fly which takes 6h 31m and costs $120 - $600.
The distance between Houston and Kirksville is 752 miles. The road distance is 890.1 miles.
The best way to get from Houston to Kirksville without a car is to bus and train via Oklahoma City which takes 22h 20m and costs $350 - $650.
It takes approximately 6h 31m to get from Houston to Kirksville, including transfers.
Yes, the driving distance between Houston to Kirksville is 890 miles. It takes approximately 15h 19m to drive from Houston to Kirksville.
There are eight+ hotels available in Kirksville.
What companies run services between Houston, TX, USA and Kirksville, MO, USA?
American Airlines, Corporate Flight Management Inc, and United Airlines fly from George Bush Intercontinental Airport (IAH) to Kirksville Regional Airport (IRK) twice daily.
- Website
- southwest.com
Flights from William P. Hobby Airport to Kansas City
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $140–800
Flights from William P. Hobby Airport to Kansas City via Dallas
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $150–850
Flights from William P. Hobby Airport to Kansas City via San Antonio
- Ave. Duration
- 4h 10m
- When
- Sunday
- Estimated price
- $170–900
Flights from William P. Hobby Airport to Kansas City via Austin
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $160–850
Flights from William P. Hobby Airport to Kansas City via New Orleans
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $180–950
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $130–750
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Austin
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $150–800
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Kansas City
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- $160–850
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Kansas City via Dallas/Ft.Worth
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $100–600
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from George Bush Intercontinental Airport to Kansas City
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $100–600
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $95–550
- Website
- contouraviation.com
Flights from George Bush Intercontinental Airport to Kirksville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Thursday, Friday, and Saturday
- Estimated price
- $200–900
Flights from George Bush Intercontinental Airport to Kirksville Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $100–550
Flights from William P. Hobby Airport to Kirksville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 25m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $280–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fort Worth to Oklahoma City
- Ave. Duration
- 4h 2m
- Frequency
- Once daily
- Estimated price
- $55–150
- Website
- Amtrak
Train from Newton Station to La Plata Station
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $90–240
- Website
- Amtrak
Train from Kansas City to La Plata Station
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Train from Kansas City to La Plata Station
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Train from Kansas City to La Plata Station
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Train from Kansas City to La Plata Station
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $35–100
- Website
- Amtrak
Train from Longview to Springfield
- Ave. Duration
- 15h 45m
- Frequency
- Once daily
- Estimated price
- $180–470
- Website
- Amtrak
Train from Galesburg Amtrak Station to La Plata Station
- Ave. Duration
- 2h 13m
- Frequency
- Once daily
- Estimated price
- $35–95
- Website
- Amtrak
- Phone
- +1 844-866-5263
- [email protected]
- Website
- Vonlane
Bus from Hyatt Regency Houston to Fort Worth
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $127–137
- Website
- Vonlane
- Adult
- $127
- adult
- $137
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Oklahoma City to Newton Station
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $45–65
- Website
- Amtrak
Bus from Houston to Longview
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $45–70
- Website
- Amtrak
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Downtown Houston to Dallas Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Dallas Bus Station to Kansas City Bus Station
- Ave. Duration
- 10h
- Frequency
- 6 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Dallas Bus Station to Kansas City Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Twice daily
- Estimated price
- $90–150
- Website
- Greyhound
Bus from Houston Bus Station to Texarkana
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
- Phone
- +1-888-875-6287
- Website
- Oats Transit
Shuttle from St. Louis to Bowling Green, Mo
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Bowling Green, Mo to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from St. Louis to Bowling Green, Mo
- Ave. Duration
- 1h 15m
- Frequency
- Twice a week
- Estimated price
- $3–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Bowling Green, Mo to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Texarkana to Kansas City
- Ave. Duration
- 9h 5m
- Frequency
- Twice daily
- Estimated price
- $110–160
- Book at
- Jefferson Lines
- Adult
- $110–160
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