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How to get fromHouston to Knoxvilleby plane, train, bus, taxi, shuttle, or car

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There are 6 ways to get from Houston to Knoxville by plane, train, bus, taxi, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly William P. Hobby Airport to Mcghee Tyson Airport

    best
    1. Fly from William P. Hobby Airport (HOU) to Mcghee Tyson Airport (TYS)plane plane HOU - TYS
    3h 50m
    $256–1,171

  2. Fly George Bush Intercontinental Airport to Chattanooga Metropolitan Airport, drive

    cheapest
    1. Fly from George Bush Intercontinental Airport (IAH) to Chattanooga Metropolitan Airport (CHA)plane plane IAH - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 49m
    $90–430

  3. Train, bus, taxi, shuttle, drive

    1. Take the train from Houston to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    40h 48m
    $944–1,383

  4. Drive  900.7 mi

    1. Drive from Houston to Knoxvillecar car 900.7 mi
    15h 33m
    $154–223

  5. Line 102 bus to George Bush Intercontinental Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Mcghee Tyson Airport (TYS)plane plane IAH - TYS
    4h 23m
    $268–1,174

  6. Fly William P. Hobby Airport to Nashville, drive

    1. Fly from William P. Hobby Airport (HOU) to Nashville (BNA)plane plane HOU - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 5m
    $110–486

William P. Hobby Airport (HOU) to Mcghee Tyson Airport (TYS) flights

Calendar30Weekly Planes
Duration3h 46mAverage Duration
Ticket$207Cheapest Price
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Comparing Your Travel Options

Map of how to get from Houston to Knoxville.ExpandLaunch map view
  • Distance: 803.4 mi
  • Duration: 3h 50m

What companies run services between Houston, TX, USA and Knoxville, TN, USA?

Allegiant Air, Southwest Airlines, and Delta fly from William P. Hobby Airport (HOU) to Mcghee Tyson Airport (TYS) 4 times a day.

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