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How to get fromHouston to Lake Cityby plane, bus, train, car, or bus (Greyhound)

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There are 9 ways to get from Houston to Lake City by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly William P. Hobby Airport to Jacksonville, bus

    best
    1. Fly from William P. Hobby Airport (HOU) to Jacksonville (JAX)plane plane HOU - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    7h 19m
    $103–501

  2. Fly William P. Hobby Airport to Gainesville Regional Airport, bus

    cheapest
    1. Fly from William P. Hobby Airport (HOU) to Gainesville Regional Airport (GNV)plane plane HOU - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 31m
    $102–467

  3. Bus

    1. Take the bus from Houston - Harrisburg Blvd to Lake Citybus bus Houston
    16h 1m
    $141–185

  4. Train, bus

    1. Take the train from Houston to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    3. Take the bus from Pascagoula to Lake Citybus bus
    20h 5m
    $341–517

  5. Drive  811.1 mi

    1. Drive from Houston to Lake Citycar car 811.1 mi
    13h 9m
    $144–207

  6. Fly George Bush Intercontinental Airport to Jacksonville, bus

    1. Fly from George Bush Intercontinental Airport (IAH) to Jacksonville (JAX)plane plane IAH - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    7h 46m
    $155–474

  7. Fly William P. Hobby Airport to Orlando, bus

    1. Fly from William P. Hobby Airport (HOU) to Orlando (MCO)plane plane HOU - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 1m
    $124–520

  8. Fly George Bush Intercontinental Airport to Orlando, bus

    1. Fly from George Bush Intercontinental Airport (IAH) to Orlando (MCO)plane plane IAH - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 34m
    $216–2,853

  9. Bus via Tallahassee (Greyhound)

    1. Take the bus from Houston Bus Station to Tallahasseebus bus Greyhound US0799
    2. Take the bus from Tallahassee to Lake City Bus Stationbus bus Greyhound US0760S
    20h 13m
    $150–231

Houston to Lake City by bus (Greyhound)

Calendar7Weekly Buses
Duration20h 13mAverage Duration
Ticket$150Cheapest Price
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Comparing Your Travel Options

Map of how to get from Houston to Lake City.ExpandLaunch map view
  • Distance: 902.2 mi
  • Duration: 7h 19m

What companies run services between Houston, TX, USA and Lake City, FL, USA?

Omnibus Express operates a bus from Houston - Harrisburg Blvd to Lake City once daily. Tickets cost $130–170 and the journey takes 14h 25m.

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