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How to get fromHouston to Saint Charlesby plane, bus, train, bus (Flixbus, Greyhound), or car

Find Transport to Saint Charles

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There are 5 ways to get from Houston to Saint Charles by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from William P. Hobby Airport

    best
    1. Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane plane HOU - STL
    4h 38m
    $151–775

  2. Drive  787.1 mi

    cheapest
    1. Drive from Houston to Saint Charlescar car 787.1 mi
    14h 26m
    $144–208

  3. Bus, train (Amtrak)

    1. Take the bus from Houston to Longviewbus bus Amtrak Thruway Connecting Service
    2. Take the train from Longview to St. Louistrain train Texas Eagle
    20h 21m
    $208–432

  4. Bus

    1. Take the bus from Downtown Houston to Memphis Bus Stationbus bus FlixBus N2211
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    22h 52m
    $174–270

  5. Line 102 bus to George Bush Intercontinental Airport, fly

    1. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane plane IAH - STL
    5h 20m
    $313–978

William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL) flights

Calendar38Weekly Planes
Duration2h 40mAverage Duration
Ticket$136Cheapest Price
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Comparing Your Travel Options

Map of how to get from Houston to Saint Charles.ExpandLaunch map view
  • Distance: 716.9 mi
  • Duration: 4h 38m

What companies run services between Houston, TX, USA and Saint Charles, MO, USA?

Southwest Airlines flies from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Downtown Houston to Saint Charles via Memphis Bus Station, St Louis Bus Station, Civic Center Transit Center, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 22h 52m.

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