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How to get fromHouston to Saint Charlesby plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 6 ways to get from Houston to Saint Charles by plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from William P. Hobby Airport

    best
    1. Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane plane HOU - STL
    4h 33m
    $165–905

  2. Line 102 bus to George Bush Intercontinental Airport, fly

    cheapest
    1. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane plane IAH - STL
    5h 8m
    $127–658

  3. Bus, train (Amtrak)

    1. Take the bus from Houston to Longviewbus bus Amtrak Thruway Connecting Service
    2. Take the train from Longview to St. Louistrain train Texas Eagle
    20h 12m
    $267–486

  4. Bus

    1. Take the bus from Downtown Houston to Memphis Bus Stationbus bus FlixBus N2211
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus FlixBus 2510
    22h 13m
    $168–285

  5. Drive 787.1 mi

    1. Drive from Houston to Saint Charlescar car 787.1 mi
    14h 26m
    $144–208

  6. Bus via Baton Rouge (Greyhound)

    1. Take the bus from Houston Bus Station to Baton Rouge Bus Stationbus bus Greyhound US0602 / ...
    2. Take the bus from Baton Rouge Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    25h 38m
    $165–316

Houston to Saint Charles by bus and train (Amtrak)

Calendar7Weekly Services
Duration20h 12mAverage Duration
Ticket$267Cheapest Price
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Questions & Answers

Map of how to get from Houston to Saint Charles.ExpandLaunch map view
  • Distance: 711.3 mi
  • Duration: 4h 33m

What companies run services between Houston, TX, USA and Saint Charles, MO, USA?

Southwest Airlines flies from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Downtown Houston to 4375 Rider Trail North Sb via Memphis Bus Station, St Louis Bus Station, Civic Center Transit Center, and North Hanley Transit Center in around 22h 13m.

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