There are 8 ways to get from Houston to Santee by plane, car, bus, taxi, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly William P. Hobby Airport to Charleston International Airport, drive
best- Fly from William P. Hobby Airport (HOU) to Charleston International Airport (CHS)plane HOU - CHS
- Drive from Charleston-Airport-CHS to Santeecar
4h 44m$141–717Fly William P. Hobby Airport to Columbia, drive
cheapest- Fly from William P. Hobby Airport (HOU) to Columbia (CAE)plane HOU - CAE
- Drive from Columbia-Airport-CAE to Santeecar
6h 24m$121–617Bus, taxi
- Take the bus from Houston - Harrisburg Blvd to Atlantabus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the bus from Camden to Sumter Bus Stopbus
- Take the taxi from Sumter Bus Stop to Santeetaxi
24h 13m$283–396Train, bus, taxi
- Take the train from Houston to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte Bus Station to Sumter Bus Stopbus
- Take the taxi from Sumter Bus Stop to Santeetaxi
34h 20m$424–828Drive 1,032 mi
- Drive from Houston to Santeecar 1,032 mi
17h 9m$189–272Fly George Bush Intercontinental Airport to Charleston International Airport, drive
- Fly from George Bush Intercontinental Airport (IAH) to Charleston International Airport (CHS)plane IAH - CHS
- Drive from Charleston-Airport-CHS to Santeecar
5h 34m$353–1,020Bus (Greyhound)
- Take the bus from Houston Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the bus from Camden to Orangeburgbus
27h 36m$249–399Bus via Athens
- Take the bus from Houston Bus Station to Atlanta Airportbus
- Take the bus from Atlanta Airport to Homewood Suites by Hilton Athensbus
- Take the bus from Athens Transit Center to Camdenbus
- Take the bus from Camden to Orangeburgbus
29h 1m$256–404
William P. Hobby Airport (HOU) to Charleston International Airport (CHS) flights
Comparing Your Travel Options
The cheapest way to get from Houston to Santee is to drive which costs $180 - $280 and takes 17h 9m.
The fastest way to get from Houston to Santee is to fly and drive which takes 4h 44m and costs $140 - $750.
No, there is no direct bus from Houston to Santee. However, there are services departing from Louisiana St @ Preston St and arriving at Orangeburg via Houston Bus Station, Atlanta Bus Station and Camden. The journey, including transfers, takes approximately 27h 36m.
The distance between Houston and Santee is 1001 miles. The road distance is 1038 miles.
The best way to get from Houston to Santee without a car is to bus and taxi which takes 24h 13m and costs $280 - $400.
It takes approximately 4h 44m to get from Houston to Santee, including transfers.
Houston to Santee bus services, operated by Greyhound USA, depart from Houston Bus Station.
Houston to Santee bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Santee is 1h ahead of Houston. It is currently 10:48 PM in Houston and 11:48 PM in Santee.
Yes, the driving distance between Houston to Santee is 1038 miles. It takes approximately 17h 9m to drive from Houston to Santee.
What companies run services between Houston, TX, USA and Santee, SC, USA?
You can take a bus from Louisiana St @ Preston St to Santee via Magnolia Transit Center, Houston Bus Station, Atlanta Bus Station, Camden, and Orangeburg in around 27h 36m.
- Website
- delta.com
Flights from William P. Hobby Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $130–700
Flights from William P. Hobby Airport to Columbia via Atlanta
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $110–600
Flights from George Bush Intercontinental Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Houston to New Orleans Union Passenger Terminal
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a week
- Estimated price
- $90–210
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Charlotte Amtrak Station
- Ave. Duration
- 18h 56m
- Frequency
- Once daily
- Estimated price
- $200–440
- Website
- Amtrak
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Atlanta
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $130–170
- Schedules at
- Omnibus Express
- Ave. Duration
- 47 min
- Estimated price
- $110–150
Columbia Discount Taxi
- Phone
- +1-803-369-5423
Columbia Discount Taxi
- Phone
- +1-803-369-5423
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Booking & Getting There
There are 41+ hotels available in Santee.







