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How to get fromHyannis to Charlestonby plane, bus, train, or car

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There are 5 ways to get from Hyannis to Charleston by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS)plane plane HYA - CHS
    6h 21m
    $141–719
  2. Bus to Boston Logan Airport, fly

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    6h 56m
    $127–628
  3. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    21h 51m
    $484–1,464
  4. Drive  969.6 mi

    1. Drive from Hyannis to Charlestoncar car 969.6 mi
    18h 29m
    $161–232
  5. Bus, train via N. Charleston SuperStop

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    24h 9m
    $451–739

Hyannis to Charleston by bus and train

Calendar14Weekly Services
Duration24h 9mAverage Duration
Ticket$451Cheapest Price
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Comparing Your Travel Options

What companies run services between Hyannis, MA, USA and Charleston, SC, USA?

American Airlines, Cape Air, and two other airlines fly from Barnstable Municipal Airport (HYA) to Charleston International Airport (CHS) every 4 hours.

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