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How to get fromHyannis to Columbusby plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

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There are 7 ways to get from Hyannis to Columbus by plane, bus (Greyhound), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to John Glenn Columbus International Airport (CMH)plane plane HYA - CMH
    5h 31m
    $129–654

  2. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Columbusbus bus
    20h 10m
    $147–275

  3. Bus, train via Brook Park

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Cleveland Amtraktrain train
    3. Take the bus from Cleveland Bus Station to Columbusbus bus
    22h 9m
    $248–531

  4. Drive 770.2 mi

    1. Drive from Hyannis to Columbuscar car 770.2 mi
    14h 27m
    $141–203

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to John Glenn Columbus International Airport (CMH)plane plane BOS - CMH
    6h 7m
    $148–993

  6. Bus via New York

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from New York Midtown to Columbusbus bus
    20h 46m
    $150–314

  7. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Cleveland Amtraktrain train
    3. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus
    24h 35m
    $298–569

Hyannis to Columbus by bus

Calendar14Weekly Buses
Duration20h 10mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Columbus.ExpandLaunch map view
  • Distance: 681.3 mi
  • Duration: 5h 31m

What companies run services between Hyannis, MA, USA and Columbus, OH, USA?

American Airlines, Cape Air, and Delta fly from Barnstable Municipal Airport (HYA) to John Glenn Columbus International Airport (CMH) 3 times a day. Alternatively, you can take a bus from Hyannis Transportation Center to Columbus via Boston, South Station, Boston, and Cleveland Bus Station in around 20h 10m.

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