There are 9 ways to get from Hyannis to Frederick by plane, bus, train, bus (Flixbus, Greyhound), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Barnstable Municipal Airport to Ronald Reagan Washington National Airport, bus
best- Fly from Barnstable Municipal Airport (HYA) to Ronald Reagan Washington National Airport (DCA)plane HYA - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
5h 57m$107–616Drive 476.1 mi
cheapest- Drive from Hyannis to Frederickcar 476.1 mi
9h 17m$87–126Bus, train via Hanover
- Take the bus from Hyannis to Bostonbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain
- Take the bus from BWI Amtrak Station to Frederick Transit Centerbus Bwi
11h 53m$174–1,584Bus
- Take the bus from Hyannis Transportation Center to Boston South Busesbus
- Take the bus from Boston to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Terminal, Baltimore, MD to Frederick Bayrunner Officebus
13h 25m$157–265Bus to Boston Logan Airport, fly to Baltimore-Washington International Airport, bus
- Take the bus from Hyannis to Bostonbus
- Fly from Boston Logan Airport (BOS) to Baltimore-Washington International Airport (BWI)plane BOS - BWI
- Take the bus from Baltimore Airport to Frederick Bus Stationbus
6h 37m$225–1,086Bus to Boston Logan Airport, fly to Washington Dulles International Airport, subway, bus
- Take the bus from Hyannis to Bostonbus
- Fly from Boston Logan Airport (BOS) to Washington Dulles International Airport (IAD)plane BOS - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
7h 44m$521–1,134Bus, train
- Take the bus from Hyannis to Bostonbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
12h 18m$116–916Bus, train #2
- Take the bus from Hyannis Transportation Center to Boston South Busesbus
- Take the train from Boston to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
12h 23m$139–317Bus via New York
- Take the bus from Hyannis to Providencebus
- Take the bus from Providence to New Yorkbus
- Take the bus from New York to Baltimorebus
- Take the bus from Baltimore Downtown Bus Terminal, Baltimore, MD to Frederick Bayrunner Officebus
13h 25m$161–288
Hyannis to Frederick by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Hyannis to Frederick is to drive which costs $85 - $130 and takes 9h 17m.
The fastest way to get from Hyannis to Frederick is to fly and bus which takes 5h 57m and costs $100 - $650.
No, there is no direct bus from Hyannis to Frederick. However, there are services departing from Hyannis Transportation Center and arriving at Frederick Bayrunner Office via Boston and Baltimore Downtown Bus Terminal, Baltimore, MD. The journey, including transfers, takes approximately 13h 25m.
The distance between Hyannis and Frederick is 460 miles. The road distance is 478.8 miles.
The best way to get from Hyannis to Frederick without a car is to bus and train via Hanover which takes 11h 53m and costs $170 - $1,600.
It takes approximately 5h 57m to get from Hyannis to Frederick, including transfers.
Hyannis to Frederick bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Frederick bus services, operated by Plymouth & Brockton, arrive at Boston South Buses station.
Yes, the driving distance between Hyannis to Frederick is 479 miles. It takes approximately 9h 17m to drive from Hyannis to Frederick.
Book your Hyannis to Frederick bus tickets online with Omio.
What companies run services between Hyannis, MA, USA and Frederick, MD, USA?
You can take a bus from Hyannis Transportation Center to Frederick Bayrunner Office via Boston, South Station, Boston, and Baltimore Downtown Bus Terminal, Baltimore, MD in around 13h 25m.
- Website
- southwest.com
Flights from Boston Logan Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $60–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $55–140
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshall
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- $45–120
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $55–140
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Washington Union Station
- Ave. Duration
- 3h 35m
- Frequency
- Hourly
- Estimated price
- $50–130
- Website
- Amtrak
Train from Boston to Washington Union Station
- Ave. Duration
- 8h 16m
- Frequency
- Every 4 hours
- Estimated price
- $110–270
- Website
- Amtrak
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
Bus from SHADY GROVE & station to Frederick Marc Station
- Ave. Duration
- 47 min
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Maryland Transit
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Booking & Getting There
There are 65+ hotels available in Frederick.





