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How to get fromHyannis to Greenvilleby plane, bus (Flixbus), bus, train, car, taxi, or bus (Greyhound)

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There are 7 ways to get from Hyannis to Greenville by plane, bus (Flixbus), bus, train, car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Greenville–Spartanburg International Airport (GSP)plane plane HYA - GSP
    5h 39m
    $176–739

  2. Drive 945.8 mi

    cheapest
    1. Drive from Hyannis to Greenvillecar car 945.8 mi
    17h 48m
    $173–250

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Gastonia, NC - Chester St.bus bus Nyc
    4. Take the bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenvillebus bus
    20h 43m
    $202–384

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    23h 59m
    $311–1,350

  5. Bus to Boston Logan Airport, fly to Asheville Regional Airport, taxi

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane plane BOS - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 36m
    $248–616

  6. Bus, train to Theodore Francis Green State Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Greenville–Spartanburg International Airport (GSP)plane plane PVD - GSP
    8h 2m
    $319–999

  7. Bus via Atlanta

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    31h 50m
    $243–576

Barnstable Municipal Airport (HYA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar6Weekly Planes
Duration8h 24mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Greenville.ExpandLaunch map view
  • Distance: 809.7 mi
  • Duration: 5h 39m

What companies run services between Hyannis, MA, USA and Greenville, SC, USA?

American Airlines flies from Barnstable Municipal Airport (HYA) to Greenville–Spartanburg International Airport (GSP) 6 times a week. Alternatively, you can take a bus from Hyannis Transportation Center to Greenville via Boston, South Station, Boston, NYC Downtown, New York, NY, Gastonia, NC - Chester St., Los Arcos Restaurant - Gastonia, and Taqueria Guadalajara - Greenville in around 20h 43m.

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