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How to get fromHyannis to Indianapolisby bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

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There are 8 ways to get from Hyannis to Indianapolis by bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Indianapolis (IND)plane plane BOS - IND
    6h 36m
    $197–978

  2. Bus, train to Theodore Francis Green State Airport, fly

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Indianapolis (IND)plane plane PVD - IND
    10h 18m
    $135–692

  3. Bus via Boston

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Indianapolisbus bus
    24h 25m
    $167–265

  4. Bus, train via Toledo

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolis, INbus bus
    25h 2m
    $225–549

  5. Drive  944.7 mi

    1. Drive from Hyannis to Indianapoliscar car 944.7 mi
    17h 25m
    $173–249

  6. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Indianapolis (IND)plane plane HYA - IND
    5h 43m
    $139–704

  7. Bus

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Yorkbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    25h 5m
    $171–293

  8. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    30h 49m
    $307–1,335

Hyannis to Indianapolis by bus

Calendar9Weekly Buses
Duration24h 25mAverage Duration
Ticket$167Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Indianapolis.ExpandLaunch map view
  • Distance: 905.6 mi
  • Duration: 6h 36m

What companies run services between Hyannis, MA, USA and Indianapolis, IN, USA?

You can take a bus from Hyannis Transportation Center to Indianapolis via Boston, South Station, Boston, and New York Midtown in around 24h 25m. Alternatively, Cape Air, Delta, and American Airlines fly from Barnstable Municipal Airport (HYA) to Indianapolis (IND) 3 times a day.

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