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How to get fromHyannis to Ithacaby bus (Flixbus), bus, train, car, or plane

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There are 9 ways to get from Hyannis to Ithaca by bus (Flixbus), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis to Bostonbus bus Bz 0947 / ...
    2. Take the bus from Boston to Ithacabus bus FlixBus 2691
    10h 14m
    $66–116

  2. Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)plane plane HYA - ITH
    8h 49m
    $55–360

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Utica Amtrak Stationtrain train
    3. Take the bus from Utica Bus Stop to Ithacabus bus
    13h 54m
    $117–241

  4. Drive 390 mi

    1. Drive from Hyannis to Ithacacar car 390 mi
    7h 21m
    $72–103

  5. Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane plane HYA - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    6h 49m
    $109–666

  6. Bus via New Haven

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Havenbus bus
    3. Take the bus from New Haven, CT - Union Station to Ithaca, NY - West Ave across from Bakers Flagpolebus bus
    11h 40m
    $117–265

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester to Ithacabus bus
    7h 16m
    $151–711

  8. Bus to Provincetown Municipal Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Syracuse Hancock International Airport (SYR)plane plane PVC - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    9h 47m
    $147–881

  9. Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 22m
    $113–673

Hyannis to Ithaca by bus

Calendar3Weekly Buses
Duration10h 14mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Ithaca.ExpandLaunch map view
  • Distance: 450.6 mi
  • Duration: 10h 14m

What companies run services between Hyannis, MA, USA and Ithaca, NY, USA?

You can take a bus from Hyannis to Ithaca via Boston in around 10h 14m. Alternatively, Cape Air, JetBlue Airways, and Delta fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) twice daily.

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