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How to get fromHyannis to Jacksonvilleby plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

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There are 7 ways to get from Hyannis to Jacksonville by plane, bus, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Jacksonville (JAX)plane plane HYA - JAX
    6h 17m
    $118–544

  2. Bus to Boston Logan Airport, fly

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Jacksonville (JAX)plane plane BOS - JAX
    7h 12m
    $117–539

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Jacksonvilletrain train
    27h 18m
    $358–1,438

  4. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York City Chinatown to Jacksonvillebus bus
    27h 54m
    $197–325

  5. Drive 1,174.4 mi

    1. Drive from Hyannis to Jacksonvillecar car 1,174.4 mi
    20h 46m
    $215–310

  6. Bus to Provincetown Municipal Airport, fly

    1. Take the bus from Hyannis to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Jacksonville (JAX)plane plane PVC - JAX
    9h 15m
    $166–696

  7. Bus via Camden

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Yorkbus bus
    3. Take the bus from New York, NY to Camdenbus bus Nyc
    4. Take the bus from Camden to Jacksonvillebus bus
    30h 32m
    $195–358

Hyannis to Jacksonville by bus and train

Calendar7Weekly Services
Duration27h 18mAverage Duration
Ticket$358Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Jacksonville.ExpandLaunch map view
  • Distance: 1,016.6 mi
  • Duration: 6h 17m

What companies run services between Hyannis, MA, USA and Jacksonville, FL, USA?

Cape Air, JetBlue Airways, and two other airlines fly from Barnstable Municipal Airport (HYA) to Jacksonville (JAX) 5 times a day. Alternatively, you can take a bus from Hyannis Transportation Center to Jacksonville via Boston, South Station, Boston, NYC Downtown, and New York City Chinatown in around 27h 54m.

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