There are 5 ways to get from Hyannis to Key West by plane, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Barnstable Municipal Airport
best- Fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW)plane HYA - EYW
18h 38m$127–512Bus
- Take the bus from Hyannis Transportation Center to Boston South Busesbus
- Take the bus from Boston to Washington Union Stationbus
- Take the bus from Washington Union Station to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
42h 41m$295–524Bus, train
- Take the bus from Hyannis Transportation Center to Boston South Stationbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
42h 58m$555–1,756Drive 1,677.2 mi
- Drive from Hyannis to Key Westcar 1,677.2 mi
29h 51m$307–443Bus to Boston Logan Airport, fly
- Take the bus from Hyannis Transportation Center to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Key West International Airport (EYW)plane BOS - EYW
7h 18m$134–479
Hyannis to Key West by bus, taxi, and foot
Questions & Answers
The cheapest way to get from Hyannis to Key West is to bus and fly which costs $130 - $480 and takes 7h 18m.
The fastest way to get from Hyannis to Key West is to bus and fly which takes 7h 18m and costs $130 - $480.
No, there is no direct bus from Hyannis to Key West. However, there are services departing from Hyannis Transportation Center and arriving at N Roosevelt & 3rd Street via Boston, Washington Union Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 42h 41m.
The distance between Hyannis and Key West is 1363 miles. The road distance is 1687 miles.
The best way to get from Hyannis to Key West without a car is to bus which takes 42h 41m and costs $290 - $550.
It takes approximately 18h 38m to get from Hyannis to Key West, including transfers.
Hyannis to Key West bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
The best way to get from Hyannis to Key West is to fly which takes 18h 38m and costs $120 - $550. Alternatively, you can bus, which costs $290 - $550 and takes 42h 41m.
Hyannis to Key West bus services, operated by Plymouth & Brockton, arrive at Boston South Buses station.
Yes, the driving distance between Hyannis to Key West is 1687 miles. It takes approximately 29h 51m to drive from Hyannis to Key West.
What companies run services between Hyannis, MA, USA and Key West, FL, USA?
American Airlines, Cape Air, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW) twice daily. Alternatively, you can take a bus from Hyannis Transportation Center to N Roosevelt & 3rd Street via Boston, Bus Terminal South Station, Boston, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 42h 41m.
- Website
- aa.com
Flights from Barnstable Municipal Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 18h 33m
- When
- Every day
- Estimated price
- $110–550
Flights from Barnstable Municipal Airport to Key West International Airport via New York La Guardia
- Ave. Duration
- 24h 40m
- When
- Every day
- Estimated price
- $110–500
Flights from Boston Logan Airport to Key West International Airport
- Ave. Duration
- 3h 58m
- When
- Saturday
- Estimated price
- $95–430
Flights from Boston Logan Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $95–430
- Website
- delta.com
Flights from Boston Logan Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $110–470
- Website
- jetblue.com
Flights from Barnstable Municipal Airport to Key West International Airport via Boston Logan Airport
- Ave. Duration
- 18h 38m
- When
- Wednesday
- Estimated price
- $110–550
Flights from Boston Logan Airport to Key West International Airport
- Ave. Duration
- 3h 59m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $75–150
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $450–900
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 (508) 746-0378
- [email protected]
- Website
- p-b.com
Bus from Hyannis Transportation Center to Boston South Buses
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com/
- One Way - Adult
- $27–35
Bus from Hyannis Transportation Center to Logan International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com/
- One Way - Adult
- $28–40
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Boston to Washington Union Station
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- $75–130
- Schedules at
- flixbus.com
Bus from Washington Union Station to Miami
- Ave. Duration
- 22h 5m
- Frequency
- 4 times a week
- Estimated price
- $160–280
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Boston to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Hyannis Transportation Center to Boston South Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $15–40
- Website
- https://peterpanbus.com
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