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How to get fromHyannis to Knoxvilleby bus, plane, train, car, or bus (Flixbus)

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There are 9 ways to get from Hyannis to Knoxville by bus, plane, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)plane plane BOS - TYS
    5h 35m
    $250–1,096

  2. Bus to Boston Logan Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane plane BOS - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 23m
    $117–501

  3. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    19h 56m
    $202–937

  4. Drive  945.6 mi

    1. Drive from Hyannis to Knoxvillecar car 945.6 mi
    16h 57m
    $173–250

  5. Fly Barnstable Municipal Airport to Mcghee Tyson Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Mcghee Tyson Airport (TYS)plane plane HYA - TYS
    4h 49m
    $267–1,153

  6. Bus, train to Theodore Francis Green State Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Mcghee Tyson Airport (TYS)plane plane PVD - TYS
    9h 19m
    $248–1,060

  7. Bus, train via Farragut

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 7m
    $260–1,038

  8. Bus

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Yorkbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 40m
    $234–346

  9. Bus via Boston

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 56m
    $237–335

Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) flights

Calendar72Weekly Planes
Duration4h 2mAverage Duration
Ticket$187Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Knoxville.ExpandLaunch map view
  • Distance: 916.7 mi
  • Duration: 5h 35m

What companies run services between Hyannis, MA, USA and Knoxville, TN, USA?

Cape Air and Allegiant Air fly from Barnstable Municipal Airport (HYA) to Mcghee Tyson Airport (TYS) 5 times a week. Alternatively, you can take a bus from Hyannis to Knoxville via Providence, New York, 47-50 Sts-Rockefeller Ctr, East Broadway, New York, and Knoxville in around 20h 40m.

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