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How to get fromHyannis to Lancasterby bus, train, car, plane, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Hyannis to Lancaster by bus, train, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Newark Penn Stationtrain train
    3. Take the train from Newark Penn Station to Elizabethtown Amtrak Stationtrain train
    12h 59m
    $132–895

  2. Drive 393.3 mi

    cheapest
    1. Drive from Hyannis to Lancastercar car 393.3 mi
    8h 1m
    $72–104

  3. Bus, train via New York

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Elizabethtown Amtrak Stationtrain train
    13h 4m
    $117–215

  4. Fly Barnstable Municipal Airport to Philadelphia International Airport, train

    1. Fly from Barnstable Municipal Airport (HYA) to Philadelphia International Airport (PHL)plane plane HYA - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    8h 29m
    $105–538

  5. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Harrisburg Bus Stationbus bus
    15h 12m
    $95–167

  6. Fly Barnstable Municipal Airport to John F. Kennedy International Airport, train

    1. Fly from Barnstable Municipal Airport (HYA) to John F. Kennedy International Airport (JFK)plane plane HYA - JFK
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Elizabethtown Amtrak Stationtrain train
    7h 45m
    $421–777

  7. Bus to Boston Logan Airport, fly to Harrisburg International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Harrisburg International Airport (MDT)plane plane BOS - MDT
    8h 57m
    $84–370

  8. Bus to Boston Logan Airport, fly to Philadelphia International Airport, train

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Philadelphia International Airport (PHL)plane plane BOS - PHL
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    9h 58m
    $228–1,049

  9. Fly Barnstable Municipal Airport to Ronald Reagan Washington National Airport, train

    1. Fly from Barnstable Municipal Airport (HYA) to Ronald Reagan Washington National Airport (DCA)plane plane HYA - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    8h 48m
    $169–727

Hyannis to Lancaster by bus and train

Calendar54Weekly Services
Duration12h 59mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Lancaster.ExpandLaunch map view
  • Distance: 501.7 mi
  • Duration: 12h 59m

What companies run services between Hyannis, MA, USA and Lancaster, PA, USA?

You can take a bus from Hyannis Transportation Center to W. Chestnut & Water St. via Boston, Bus Terminal South Station, Boston, Newark Penn Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 15h 12m.

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