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How to get fromHyannis to Myrtle Beachby bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 8 ways to get from Hyannis to Myrtle Beach by bus, plane, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Boston Logan Airport, fly to Myrtle Beach

    best
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    5h 17m
    $96–430

  2. Fly Barnstable Municipal Airport to Myrtle Beach

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR)plane plane HYA - MYR
    5h 1m
    $93–446

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    22h 26m
    $231–1,145

  4. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Richmondbus bus
    3. Take the bus from Richmond to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    24h 40m
    $169–270

  5. Drive  886.3 mi

    1. Drive from Hyannis to Myrtle Beachcar car 886.3 mi
    16h 55m
    $162–234

  6. Bus, train to Theodore Francis Green State Airport, fly to Myrtle Beach

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Myrtle Beach (MYR)plane plane PVD - MYR
    7h 24m
    $144–314

  7. Bus to Boston Logan Airport, fly to Wilmington International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Wilmington International Airport (ILM)plane plane BOS - ILM
    3. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 45m
    $126–553

  8. Bus via New York

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Yorkbus bus
    3. Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    24h 56m
    $156–243

Hyannis to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration22h 26mAverage Duration
Ticket$231Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Myrtle Beach.ExpandLaunch map view
  • Distance: 815.3 mi
  • Duration: 5h 17m

What companies run services between Hyannis, MA, USA and Myrtle Beach, SC, USA?

You can take a bus from Hyannis Transportation Center to Myrtle Beach Bus Station via Boston, South Station, Boston, Richmond, Richmond, and Raleigh Bus Station in around 24h 40m. Alternatively, Cape Air, American Airlines, and two other airlines fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR) once daily.

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