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How to get fromHyannis to Myrtle Beachby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Hyannis to Myrtle Beach by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR)plane plane HYA - MYR
    4h 26m
    $89–406

  2. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Camdenbus bus Nyc
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    26h 49m
    $165–255

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    28h 11m
    $317–1,265

  4. Drive 886.3 mi

    1. Drive from Hyannis to Myrtle Beachcar car 886.3 mi
    16h 54m
    $162–234

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    5h 38m
    $104–390

  6. Bus via Raleigh

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    28h 55m
    $200–434

Hyannis to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration28h 11mAverage Duration
Ticket$317Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Myrtle Beach.ExpandLaunch map view
  • Distance: 728.2 mi
  • Duration: 4h 26m

What companies run services between Hyannis, MA, USA and Myrtle Beach, SC, USA?

American Airlines, Cape Air, and Delta fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR) 5 times a week. Alternatively, you can take a bus from Hyannis Transportation Center to Myrtle Beach Bus Station via Boston, Bus Terminal South Station, Boston, NYC Downtown, New York, NY, and Camden in around 26h 49m.

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