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How to get fromHyannis to Niagara Fallsby plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

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There are 7 ways to get from Hyannis to Niagara Falls by plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport, bus

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    5h 36m
    $99–577

  2. Drive  526.4 mi

    cheapest
    1. Drive from Hyannis to Niagara Fallscar car 526.4 mi
    9h 21m
    $97–139

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    14h 18m
    $104–157

  4. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    16h 14m
    $142–464

  5. Bus to Boston Logan Airport, fly, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    6h 7m
    $99–583

  6. Bus to Provincetown Municipal Airport, fly, bus

    1. Take the bus from Hyannis to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 37m
    $149–793

  7. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Niagara Falls USAbus bus
    15h 59m
    $109–165

Hyannis to Niagara Falls by bus

Calendar7Weekly Buses
Duration14h 18mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Niagara Falls.ExpandLaunch map view
  • Distance: 471.4 mi
  • Duration: 5h 36m

What companies run services between Hyannis, MA, USA and Niagara Falls, NY, USA?

You can take a bus from Hyannis Transportation Center to Main Street & Pine Avenue via Boston, South Station, Boston, Buffalo, and Ellicott Street & MTC Static in around 14h 18m.

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