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How to get fromHyannis to Niagara Fallsby plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

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There are 9 ways to get from Hyannis to Niagara Falls by plane, bus, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Buffalo Niagara International Airport, line 40 bus

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Buffalo Niagara International Airport (BUF)plane plane HYA - BUF
    2. Take the bus from Ellicott Street & MTC Static to Main Street & Pine Avenuebus bus
    6h 17m
    $100–572

  2. Drive  526.4 mi

    cheapest
    1. Drive from Hyannis to Niagara Fallscar car 526.4 mi
    9h 21m
    $97–139

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    14h 18m
    $99–157

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    16h 30m
    $155–475

  5. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    7h 22m
    $111–591

  6. Bus to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Hyannis to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane plane PVC - BUF
    8h 43m
    $138–741

  7. Bus to Boston Logan Airport, fly to Rochester, train

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    8h
    $166–878

  8. Bus to Boston Logan Airport, fly to Toronto Island Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Toronto Island Airport (YTZ)plane plane BOS - YTZ
    3. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    8h 18m
    $135–561

  9. Bus via Ithaca

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Niagara Falls USAbus bus
    15h 59m
    $109–165

Hyannis to Niagara Falls by bus

Calendar7Weekly Buses
Duration14h 18mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Niagara Falls.ExpandLaunch map view
  • Distance: 474.8 mi
  • Duration: 6h 17m

What companies run services between Hyannis, MA, USA and Niagara Falls, NY, USA?

You can take a bus from Hyannis Transportation Center to Main Street & Pine Avenue via Boston, South Station, Boston, Buffalo, and Ellicott Street & MTC Static in around 14h 18m.

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