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How to get fromHyannis to Presque Isleby plane, bus (Amtrak), car, bus, ferry, bus (Flixbus, Greyhound), or train

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There are 8 ways to get from Hyannis to Presque Isle by plane, bus (Amtrak), car, bus, ferry, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI)plane plane HYA - PQI
    5h 44m
    $66–369

  2. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    11h 21m
    $93–140

  3. Drive  461.1 mi

    1. Drive from Hyannis to Presque Islecar car 461.1 mi
    8h 10m
    $85–122

  4. Bus to Provincetown Municipal Airport, fly

    1. Take the bus from Hyannis to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Presque Isle (PQI)plane plane PVC - PQI
    9h 7m
    $103–489

  5. Ferry to Martha'S Vineyard Airport, fly

    1. Take the ferry from Ocean Street Terminal, Hyannis, MA to Dockside Marina - Oak Bluffs, Martha's Vineyard, MAferry ferry
    2. Fly from Martha'S Vineyard Airport (MVY) to Presque Isle (PQI)plane plane MVY - PQI
    7h 14m
    $89–420

  6. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Presque Isle (PQI)plane plane BOS - PQI
    4h 37m
    $74–371

  7. Bus via Bangor

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Bangor Park & Ridebus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 50m
    $84–144

  8. Train, bus

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Portlandtrain train
    3. Take the bus from Portland Transportation Center to Bangor Transportation Centerbus bus
    4. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    13h 44m
    $104–203

Hyannis to Presque Isle by bus

Calendar7Weekly Buses
Duration11h 21mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Presque Isle.ExpandLaunch map view
  • Distance: 366.5 mi
  • Duration: 5h 44m

What companies run services between Hyannis, MA, USA and Presque Isle, ME, USA?

Cape Air and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI) 3 times a week. Alternatively, you can take a bus from Hyannis Transportation Center to Presque Isle, Maine via Boston, South Station, Boston, MA - South Station, Bangor Transportation Center, and Bangor, ME in around 11h 21m.

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