Rome2Rio

How to get fromHyannis to San Diegoby plane, bus, train, bus (Greyhound, Amtrak), or car

Find Transport to San Diego

See all options

There are 7 ways to get from Hyannis to San Diego by plane, bus, train, bus (Greyhound, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN)plane plane HYA - SAN
    7h 56m
    $270–1,100

  2. Bus to Boston Logan Airport, fly

    cheapest
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN)plane plane BOS - SAN
    9h 10m
    $198–436

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to South Station Transp. Ctrbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d
    $1,087–2,305

  4. Bus

    1. Take the bus from Hyannis Transportation Center to South Station Transp. Ctrbus bus
    2. Take the bus from Boston to New Yorkbus bus
    3. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles to San Diegobus bus
    3d 3h
    $572–1,140

  5. Drive 2,983.8 mi

    1. Drive from Hyannis to San Diegocar car 2,983.8 mi
    2d 2h
    $545–787

  6. Bus to Provincetown Municipal Airport, fly

    1. Take the bus from Hyannis Transportation Center to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to San Diego International Airport (SAN)plane plane PVC - SAN
    11h 42m
    $283–1,129

  7. Bus, train via New York

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d
    $920–1,954

Hyannis to San Diego by bus and train

Calendar7Weekly Services
Duration3dAverage Duration
Ticket$1,087Cheapest Price
See schedules

Questions & Answers

Map of how to get from Hyannis to San Diego.ExpandLaunch map view
  • Distance: 2,620.8 mi
  • Duration: 7h 56m

What companies run services between Hyannis, MA, USA and San Diego, CA, USA?

Cape Air, JetBlue Airways, and Alaska Airlines, Inc. fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN) twice daily. Alternatively, you can take a bus from Hyannis Transportation Center to San Diego via Boston, New York, Port Authority Bus Terminal, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 3d 3h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers