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How to get fromHyannis to San Franciscoby plane, bus, train, bus (Greyhound), or car

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There are 8 ways to get from Hyannis to San Francisco by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to San Francisco International Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to San Francisco International Airport (SFO)plane plane HYA - SFO
    8h 36m
    $190–680

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to South Station Transp. Ctrbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Richmondtrain train
    3d 7h
    $1,111–2,342

  3. Bus

    1. Take the bus from Hyannis Transportation Center to South Station Transp. Ctrbus bus
    2. Take the bus from Boston to New Yorkbus bus
    3. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    3d 8h
    $582–1,185

  4. Drive 3,138.3 mi

    1. Drive from Hyannis to San Franciscocar car 3,138.3 mi
    2d 2h
    $573–828

  5. Bus to Boston Logan Airport, fly to San Francisco International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to San Francisco International Airport (SFO)plane plane BOS - SFO
    10h 7m
    $237–598

  6. Bus to Boston Logan Airport, fly to Oakland International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Oakland International Airport (OAK)plane plane BOS - OAK
    11h 48m
    $273–994

  7. Bus to Provincetown Municipal Airport, fly to San Francisco International Airport

    1. Take the bus from Hyannis Transportation Center to Provincetownbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to San Francisco International Airport (SFO)plane plane PVC - SFO
    12h 29m
    $202–741

  8. Bus, train via New York

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the train from Chicago Union Station to Richmondtrain train
    3d 8h
    $944–2,000

Hyannis to San Francisco by bus, train, and subway

Calendar7Weekly Services
Duration3d 7hAverage Duration
Ticket$1,111Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to San Francisco.ExpandLaunch map view
  • Distance: 2,757.9 mi
  • Duration: 8h 36m

What companies run services between Hyannis, MA, USA and San Francisco, CA, USA?

Cape Air and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to San Francisco International Airport (SFO) 4 times a day. Alternatively, you can take a bus from Hyannis Transportation Center to San Francisco Bus Station via Boston, New York, Port Authority Bus Terminal, St Louis Bus Station, and Los Angeles Union Station in around 3d 8h.

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