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How to get fromHyannis to Sanfordby bus (Greyhound), bus, train, train (Amtrak), car, or plane

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There are 7 ways to get from Hyannis to Sanford by bus (Greyhound), bus, train, train (Amtrak), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Boston

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus Hyannis
    2. Take the bus from Boston to Wells Transportation Centerbus bus Greyhound US0265s
    4h 41m
    $66–116

  2. Drive 155 mi

    cheapest
    1. Drive from Hyannis to Sanfordcar car 155 mi
    3h 15m
    $29–41

  3. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus Bz 0947 / ...
    2. Take the train from Boston to Wellstrain train Downeaster
    4h 58m
    $84–151

  4. Train

    1. Take the train from Hyannis to South Stationtrain train CapeFLYER
    2. Take the train from Boston to Wellstrain train Downeaster
    5h 56m
    $74–135

  5. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Wells Transportation Centerbus bus Greyhound US0265s
    4h 51m
    $78–113

  6. Bus, train via Woburn

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Woburn Amtrak Station to Wellstrain train Downeaster
    6h 1m
    $99–150

  7. Fly, train

    1. Fly from Barnstable Municipal Airport (HYA) to Boston Logan Airport (BOS)plane plane HYA - BOS
    2. Take the train from Woburn Amtrak Station to Wellstrain train
    4h 31m
    $193–416

Barnstable Municipal Airport (HYA) to Boston Logan Airport (BOS) flights

Calendar50Weekly Planes
Duration1h 37mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Sanford.ExpandLaunch map view
  • Distance: 161.5 mi
  • Duration: 4h 41m

What companies run services between Hyannis, MA, USA and Sanford, ME, USA?

You can take a bus from Hyannis Transportation Center to Sanford via Boston South Station, Boston, and Wells Transportation Center in around 4h 41m. Alternatively, you can take a train from Hyannis to Sanford via South Station, Downtown Crossing, North Station, Boston, and Wells in around 5h 56m.

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