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How to get fromHyannis to Syracuseby bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Flixbus)

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There are 6 ways to get from Hyannis to Syracuse by bus (Greyhound, Flixbus), bus, train, car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the bus from Boston to Syracuse Bus Stationbus bus Greyhound US0171 / ...
    9h 15m
    $72–130

  2. Drive 369.1 mi

    cheapest
    1. Drive from Hyannis to Syracusecar car 369.1 mi
    6h 37m
    $68–98

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus Hyannis - South Shore to Logan Airport
    2. Take the train from Boston to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    11h 51m
    $137–265

  4. Fly from Barnstable Municipal Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane plane HYA - SYR
    5h 49m
    $107–660

  5. Bus via West Albany

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Albanybus bus
    3. Take the bus from Albany to Syracusebus bus
    10h 35m
    $78–125

  6. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    5h 46m
    $102–598

Hyannis to Syracuse by bus

Calendar34Weekly Buses
Duration9h 15mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Syracuse.ExpandLaunch map view
  • Distance: 389.6 mi
  • Duration: 9h 15m

What companies run services between Hyannis, MA, USA and Syracuse, NY, USA?

You can take a bus from Hyannis Transportation Center to Syracuse Bus Station via Boston, South Station and Boston in around 9h 15m. Alternatively, American Airlines, Cape Air, and two other airlines fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR) 3 times a day.

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