There are 5 ways to get from Iguazu Falls to Santa Cruz by plane, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Foz Do Iguaçu / Cataratas International Airport
best- Fly from Foz Do Iguaçu / Cataratas International Airport (IGU) to Viru Viru International Airport (VVI)plane IGU - VVI
6h 46m$324–705Drive, bus
cheapest- Drive from Iguazu Falls to Plaza Jesuitica Shoppingcar
- Take the bus from Plaza Jesuitica Shopping to Terminal de Ómnibus de Asunciónbus
- Take the bus from Terminal de Ómnibus de Asunción to Terminal Bimodalbus
26h 49m$84–125Drive 1,674.6 km
- Drive from Iguazu Falls to Santa Cruz de la Sierracar 1,674.6 km
24h 31m$169–244Fly from Cataratas Del Iguazú International Airport
- Fly from Cataratas Del Iguazú International Airport (IGR) to Viru Viru International Airport (VVI)plane IGR - VVI
6h 54m$376–618Bus
- Take the bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedobus
- Take the bus from Coronel Oviedo to Terminal de Ómnibus de Asunciónbus
- Take the bus from Terminal de Ómnibus de Asunción to Terminal Bimodalbus
29h 6m$95–13,126
Foz Do Iguaçu / Cataratas International Airport (IGU) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Iguazu Falls to Santa Cruz is to drive and bus which costs $80 - $130 and takes 26h 49m.
The fastest way to get from Iguazu Falls to Santa Cruz is to fly which takes 6h 46m and costs $320 - $750.
No, there is no direct bus from Iguazu Falls to Santa Cruz. However, there are services departing from Cataratas Argentinas and arriving at Terminal Bimodal via Terminal de Ómnibus de Puerto Iguazú, Terminal de Ómnibus de Ciudad del Este, Coronel Oviedo and Terminal de Ómnibus de Asunción. The journey, including transfers, takes approximately 29h 6m.
The distance between Iguazu Falls and Santa Cruz is 1306 km. The road distance is 1674.6 km.
The best way to get from Iguazu Falls to Santa Cruz without a car is to bus which takes 29h 6m and costs $95 - $14,000.
It takes approximately 6h 46m to get from Iguazu Falls to Santa Cruz, including transfers.
Iguazu Falls to Santa Cruz bus services, operated by Crucero del Este, depart from Terminal de Ómnibus de Ciudad del Este station.
The best way to get from Iguazu Falls to Santa Cruz is to fly which takes 6h 46m and costs $320 - $750. Alternatively, you can bus, which costs $95 - $14,000 and takes 29h 6m.
Iguazu Falls to Santa Cruz bus services, operated by Crucero del Este, arrive at Coronel Oviedo station.
Santa Cruz is 1h behind Iguazu Falls. It is currently 2:14 PM in Iguazu Falls and 1:14 PM in Santa Cruz.
What companies run services between Iguazu Falls, Argentina and Santa Cruz, Bolivia?
Gol Transportes Aéreos, Boliviana de Aviación, and LATAM Chile fly from Foz Do Iguaçu / Cataratas International Airport (IGU) to Viru Viru International Airport (VVI) 4 times a day. Alternatively, you can take a bus from Cataratas Argentinas to Santa Cruz de la Sierra via Terminal de Ómnibus de Puerto Iguazú, Terminal de Ómnibus de Ciudad del Este, Coronel Oviedo, Terminal de Ómnibus de Asunción, and Terminal Bimodal in around 29h 6m.
- Website
- boa.bo
Flights from Foz Do Iguaçu / Cataratas International Airport to Viru Viru International Airport via Sao Paulo
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $370–650
Flights from Foz Do Iguaçu / Cataratas International Airport to Viru Viru International Airport via Rio De Janeiro-Galeao
- Ave. Duration
- 6h 25m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $370–650
Flights from Cataratas Del Iguazú International Airport to Viru Viru International Airport via Ezeiza
- Ave. Duration
- 6h 53m
- When
- Tuesday and Sunday
- Estimated price
- $250–750
- Website
- voegol.com.br
Flights from Foz Do Iguaçu / Cataratas International Airport to Viru Viru International Airport via Sao Paulo
- Ave. Duration
- 6h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–700
- Website
- aerolineas.com.ar
Flights from Cataratas Del Iguazú International Airport to Viru Viru International Airport via Buenos Aires Jorge Newbery
- Ave. Duration
- 6h 22m
- When
- Monday and Friday
- Estimated price
- $200–700
- Phone
- +595 21 289 1000
- [email protected]
- Website
- nsa.com.py
Bus from Plaza Jesuitica Shopping to Terminal de Ómnibus de Asunción
- Ave. Duration
- 4h 53m
- Frequency
- Every 4 hours
- Estimated price
- $1–28
- Schedules at
- nsa.com.py
- Book at
- nsa.com.py
- Phone
- +595 983 781493
Bus from Terminal de Ómnibus de Asunción to Terminal Bimodal
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- $84
- Schedules at
- facebook.com
Bus from Terminal de Ómnibus de Asunción to Terminal Bimodal
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- $84
- Schedules at
- facebook.com
- Phone
- +595 9 8236 7953
- [email protected]
- Website
- facebook.com
Bus from Terminal de Ómnibus de Asunción to Terminal Bimodal
- Ave. Duration
- 24h
- Frequency
- 3 times a week
- Estimated price
- $75
- Schedules at
- facebook.com
Bus from Terminal de Ómnibus de Asunción to Terminal Bimodal
- Ave. Duration
- 24h
- Frequency
- 3 times a week
- Estimated price
- $75
- Schedules at
- facebook.com
- Phone
- +595 986 280001
- [email protected]
- Website
- facebook.com
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 3h 10m
- Frequency
- Every 3 hours
- Schedules at
- plataforma10.com.py
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 3h 50m
- Frequency
- Every 3 hours
- Schedules at
- plataforma10.com.py
- Phone
- +595 21 557 310
- [email protected]
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 3h 34m
- Frequency
- Every 4 hours
- Estimated price
- $10–14
- Schedules at
- facebook.com
- Phone
- +595 541 40518
- [email protected]
- Website
- empresaguairena.com.py
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 3h 34m
- Frequency
- 4 times a day
- Estimated price
- $9–13
- Schedules at
- empresaguairena.com.py
- Book at
- mbp.mibus.com.py
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 2h 20m
- Frequency
- Every 2 hours
- Estimated price
- $6–10
- Schedules at
- empresaguairena.com.py
- Book at
- mbp.mibus.com.py
- Phone
- +595 0983 801623
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–12
- Schedules at
- plataforma10.com.py
- Semicama
- $8–12
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a day
- Estimated price
- $5–8
- Schedules at
- plataforma10.com.py
- Semicama
- $5–8
- Phone
- +595 21 7283500
- [email protected]
- Website
- expresoparaguay.com.py
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $17–28,000
- Schedules at
- expresoparaguay.com.py
- Book at
- expresoparaguay.com.py
- Cama
- $23,000–28,000
- Semicama
- $17–22
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $14–23,000
- Schedules at
- expresoparaguay.com.py
- Book at
- expresoparaguay.com.py
- Cama
- $18,000–23,000
- Semicama
- $14–19
- Phone
- +595 21 238 1111
- [email protected]
- Website
- lasantaniana.com.py
Bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedo
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $11–15
- Schedules at
- lasantaniana.plataforma10.com.ar
- Book at
- lasantaniana.plataforma10.com.ar
- Semicama
- $11–15
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 2h 2m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Schedules at
- lasantaniana.plataforma10.com.ar
- Book at
- lasantaniana.plataforma10.com.ar
- Semicama
- $8–11
- Phone
- +595 3 3627 3059
- [email protected]
- Website
- facebook.com
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $8
- Book at
- plataforma10.com.py
- Phone
- +595 0342 222 347
Bus from Coronel Oviedo to Terminal de Ómnibus de Asunción
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Schedules at
- plataforma10.com.py
- Book at
- plataforma10.com.py
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More Questions & Answers
Yes, the driving distance between Iguazu Falls to Santa Cruz is 1675 km. It takes approximately 24h 31m to drive from Iguazu Falls to Santa Cruz.
There are 728+ hotels available in Santa Cruz.











